Review on anti-tumor effect of triterpene acid compounds

被引：77
|
作者：
Zhang, Weisan [1 ]
Men, Xiaoyan [2 ]
Lei, Ping [1 ]
机构：
[1] Tianjin Med Univ, Gen Hosp, Dept Geriatr, Tianjin Geriatr Inst, Tianjin 300052, Peoples R China
[2] Tianjin Med Univ, Canc Hosp, Dept Internal Med 6, Tianjin 300052, Peoples R China
来源：
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS | 2014年 / 10卷 / 05期
关键词：
Antitumor activity; apoptosis; mechanism; proliferation; triterpene acid; CELL-CYCLE ARREST; LANOSTANE-TYPE TRITERPENOIDS; PANCREATIC-CANCER CELLS; NF-KAPPA-B; BETULINIC ACID; URSOLIC ACID; OLEANOLIC ACID; INHIBITS PROLIFERATION; ESTER DERIVATIVES; INONOTUS-OBLIQUUS;
D O I：
10.4103/0973-1482.139746
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Recent studies have found that triterpene acid type compounds has many effects including antiinflammatory, regulating blood sugar level, antiviral and antitumor activity. More importantly, triterpene acid type compounds has become one of the most popular topics recently because its selective toxic effects on cancer cells and harmless to normal cells at the same time. This review summarized the antitumor activity and the mechanism of triterpene acid type compounds, providing guideline for further research and development of new antitumor natural products.
引用
收藏
页码：14 / 19
页数：6
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