Apotirucallane protolimonoids from the Chinese mangrove Xylocarpus granatum Koenig

被引：19
|
作者：
Zhou, Zhen-Fang [1 ]
Taglialatela-Scafati, Orazio [2 ]
Liu, Hai-Li [1 ]
Gu, Yu-Cheng [3 ]
Kong, Ling-Yi [4 ]
Guo, Yue-Wei [1 ]
机构：
[1] Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
[2] Univ Naples Federico II, Dipartimento Farm, I-80131 Naples, Italy
[3] Syngenta Jealotts Hill Int Res Ctr, Guildford RG42 6EY, Berks, England
[4] China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Peoples R China
来源：
FITOTERAPIA | 2014年 / 97卷
关键词：
Xylocarpus granatum; Protolimonoid; Apotirucallane; Cytotoxicity; LIMONOIDS;
D O I：
10.1016/j.fitote.2014.06.009
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of previously unreported compounds including seven new apotirucallane protolimonoids, xylogranatumines A-G (1-7), were isolated together with three known analogues (8-10) from the twigs and leaves of the Chinese mangrove, Xylocarpus granatum. The structures of these new compounds were elucidated by extensive spectroscopic analysis including 1D and 2D NMR and high-resolution electrospray ionization mass spectrometry (HRESIMS) and by comparison with those of related known compounds in the literature. Xylogranatumine F (6) exhibited cytotoxic activity against A549 tumor cell in vitro. (c) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：192 / 197
页数：6
相关论文
共 50 条
  • [31] Xylocarpins A and B, two new mexicanolides from the seeds of a Chinese mangrove Xylocarpus granatum:: NMR investigation in mixture
    Li, Minyi
    Wu, Jun
    Zhang, Si
    Xiao, Qiang
    Li, Qingxin
    MAGNETIC RESONANCE IN CHEMISTRY, 2007, 45 (08) : 705 - 709
  • [32] Xylogranatinin, a new pyrido[1,2-a]pyrazine alkaloid from the fruit of a Chinese mangrove Xylocarpus granatum
    Zhou, Yuan
    Wu, Jun
    Zou, Kun
    CHEMISTRY OF NATURAL COMPOUNDS, 2007, 43 (04) : 426 - 428
  • [33] Xylogranatins F-R:: Antifeedants from the chinese mangrove, Xylocarpus granatum, a new biogenetic pathway to tetranortriterpenoids
    Wu, Jun
    Zhang, Si
    Bruhn, Torsten
    Xiao, Qiang
    Ding, Haixin
    Bringmann, Gerhard
    CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (04) : 1129 - 1144
  • [34] 7-ALPHA-ACETOXYDIHYDRONOMILIN AND MEXICANOLIDE - LIMONOIDS FROM XYLOCARPUS-GRANATUM (KOENIG) - COMMENT
    NG, AS
    FALLIS, AG
    CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1979, 57 (23): : 3088 - 3089
  • [35] Xylogranatinin, a new pyrido[1, 2-a]pyrazine alkaloid from the fruit of a Chinese mangrove Xylocarpus granatum
    Yuan Zhou
    Jun Wu
    Kun Zou
    Chemistry of Natural Compounds, 2007, 43 : 426 - 428
  • [36] Two new limonoids with a 3-O-β-tigloyl group from the seeds of the Chinese mangrove Xylocarpus granatum
    Wu, Jun
    Li, Minyi
    Zhang, Si
    Xiao, Qiang
    Li, Qingxin
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2007, 62 (06): : 859 - 862
  • [37] Granatumins A-G, Limonoids from the Seeds of a Krishna Mangrove, Xylocarpus granatum
    Li, Min-Yi
    Yang, Xiao-Bo
    Pan, Jian-Yu
    Feng, Gang
    Xiao, Qiang
    Sinkkonen, Jari
    Satyanandamurty, Tirumani
    Wu, Jun
    JOURNAL OF NATURAL PRODUCTS, 2009, 72 (12): : 2110 - 2114
  • [38] Factors limiting the intertidal distribution of the mangrove species Xylocarpus granatum
    James A. Allen
    Ken W. Krauss
    Robert D. Hauff
    Oecologia, 2003, 135 : 110 - 121
  • [39] Bioactivity guided isolation of antidiabetic and antioxidant compound from Xylocarpus granatum J. Koenig bark
    Swagat Kumar Das
    Dibyajyoti Samantaray
    Sudhir Kumar Sahoo
    Sukanta Kumar Pradhan
    Luna Samanta
    Hrudayanath Thatoi
    3 Biotech, 2019, 9
  • [40] Factors limiting the intertidal distribution of the mangrove species Xylocarpus granatum
    Allen, JA
    Krauss, KW
    Hauff, RD
    OECOLOGIA, 2003, 135 (01) : 110 - 121
12345