Selectively substituted thiophenes and indoles by a tandem palladium-catalyzed multicomponent reaction

被引：74
|
作者：
Mitsudo, Koichi [1 ]
Thansandote, Praew [1 ]
Wilhelm, Thorsten [1 ]
Mariampillai, Brian [1 ]
Lautens, Mark [1 ]
机构：
[1] Univ Toronto, Dept Chem, Davenport Res Labs, Toronto, ON M5S 3H6, Canada
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 18期
关键词：
D O I：
10.1021/ol061373t
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A variety of di- and trisubstituted thiophenes were synthesized by a one-pot palladium- catalyzed ortho-alkylation sequence terminated by either Heck or C-H coupling. Initial results toward the functionalization of indoles are also presented.
引用
收藏
页码：3939 / 3942
页数：4
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