Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

被引：0

作者：

Wang, Tianshi ^{[1
]}

Pfeiffer, Tom ^{[2
]}

Daemen, Joost ^{[1
]}

Mastik, Frits ^{[1
]}

Wieser, Wolfgang ^{[3
]}

Van der Steen, A. F. W. ^{[1
,4
,5
]}

Huber, Robert ^{[2
]}

Van Soest, Gijs ^{[1
]}

机构：

[1] Erasmus MC, Thoraxctr, POB 2040, NL-3000 CA Rotterdam, Netherlands

[2] Univ Lubeck, Inst Biomed Opt, Peter Monnik Weg 4, D-23562 Lubeck, Germany

[3] Optores GmbH, Gollierstr 70, D-80339 Munich, Germany

[4] Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China

[5] Delft Univ Technol, Dept Imaging Sci & Technol, Postbus 5, NL-2600 AA Delft, Netherlands

来源：

DIAGNOSTIC AND THERAPEUTIC APPLICATIONS OF LIGHT IN CARDIOLOGY 2019 | 2019年 / 10855卷

关键词：

SPECKLE DECORRELATION; BLOOD-FLOW; HIGH-SPEED;

D O I：

10.1117/12.2506151

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/ s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

引用

页数：5

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