3D high-resolution contrast enhanced MRI of carotid atheroma - a technical update

Objective: Development of a fast 3D high-resolution magnetic resonance imaging (MRI) protocol for improved carotid artery plaque imaging. Methods: Two patients with carotid atherosclerosis disease underwent 3D high-resolution MRI which included time-of-flight and T-1-weighted variable flip angle, fast-spin-echo (FSE) imaging, pre- and post-intravenous gadolinium-based contrast agent administration. Results: Good quality images with intrinsic blood suppression were obtained pre- and post-contrast administration using a 3D FSE sequence. The plaque burden, lipid core volume, hemorrhage volume and fibrous cap thickness were well determined. Conclusions: 3D high-resolution MR imaging of carotid plaque using TOF and 3D FSE can achieve high isotropic resolution, large coverage, and excellent image quality within a short acquisition time. (C) 2014 Elsevier Inc. All rights reserved.