Reduced expression of the multifunctional apolipoprotein E receptor LR11 plays an important role in Alzheimer's disease pathogenesis.

被引:0
|
作者
Gearing, M
Lah, JJ
Sager, KL
Offer, K
Dodson, SE
Carter, SC
Bennett, DA
Mufson, EJ
Levey, AI
机构
[1] Emory Univ, Sch Med, Dept Pathol & Lab Med, Atlanta, GA 30322 USA
[2] Emory Univ, Sch Med, Ctr Neurodegenerat Dis, Atlanta, GA 30322 USA
[3] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA 30322 USA
[4] Emory Univ, Grad Program Neurosci, Atlanta, GA 30322 USA
[5] Rush Univ, Ctr Med, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
[6] Rush Univ, Ctr Med, Dept Neurol Sci, Chicago, IL 60612 USA
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
172
引用
收藏
页码:553 / 553
页数:1
相关论文
共 50 条
  • [21] Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease
    Dodson, Sara E.
    Andersen, Olav M.
    Karmali, Vinit
    Fritz, Jason J.
    Cheng, Dongmei
    Peng, Junmin
    Levey, Allan I.
    Willnow, Thomas E.
    Lah, James J.
    JOURNAL OF NEUROSCIENCE, 2008, 28 (48): : 12877 - 12886
  • [22] The Role of Apolipoprotein E Isoforms in Alzheimer's Disease
    Roda, Alejandro R.
    Montoliu-Gaya, Laia
    Villegas, Sandra
    JOURNAL OF ALZHEIMERS DISEASE, 2019, 68 (02) : 459 - 471
  • [23] The Roles of Apolipoprotein E, Lipids, and Glucose in the Pathogenesis of Alzheimer's Disease
    Shinohara, Mitsuru
    Sato, Naoyuki
    DIABETES MELLITUS: A RISK FACTOR FOR ALZHEIMER'S DISEASE, 2019, 1128 : 85 - 101
  • [24] Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease
    Poirier, J
    TRENDS IN MOLECULAR MEDICINE, 2003, 9 (03) : 94 - 101
  • [25] The Important Interface Between Apolipoprotein E and Neuroinflammation in Alzheimer's Disease
    Kloske, Courtney M.
    Wilcock, Donna M.
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [26] Distortion of allelic expression of apolipoprotein E in Alzheimer's disease
    Lambert, JC
    PerezTur, J
    Dupire, MJ
    Galasko, D
    Mann, D
    Amouyel, P
    Hardy, J
    Delacourte, A
    ChartierHarlin, MC
    HUMAN MOLECULAR GENETICS, 1997, 6 (12) : 2151 - 2154
  • [27] Apolipoprotein E and Alzheimer's disease - A role in amyloid catabolism
    Poirier, J
    ALZHEIMERS DISEASE: A COMPENDIUM OF CURRENT THEORIES, 2000, 924 : 81 - 90
  • [28] The role of apolipoprotein E testing in the diagnosis of Alzheimer's disease
    Galasko, D
    WESTERN JOURNAL OF MEDICINE, 1998, 168 (04): : 264 - 265
  • [29] Apolipoprotein E in the brain and its role in Alzheimer's disease
    Poirier, J
    JOURNAL OF PSYCHIATRY & NEUROSCIENCE, 1996, 21 (02): : 128 - 134
  • [30] Aβ-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease
    Huang, Yadong
    TRENDS IN MOLECULAR MEDICINE, 2010, 16 (06) : 287 - 294