Medical applications of systems biology

被引：1
|
作者：
Demongeot, Jacques [1 ]
机构：
[1] Univ Grenoble 1, TIMC IMAG UMR UJF CNRS 5525, Fac Med, F-38700 La Tronche, France
来源：
M S-MEDECINE SCIENCES | 2009年 / 25卷 / 6-7期
关键词：
BOUNDARY-CONDITIONS; NEGATIVE FEEDBACK; PHASE-TRANSITIONS; GENETIC NETWORKS; DYNAMICS; MODELS; ROLES; RNA;
D O I：
10.1051/medsci/2009256-7588
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We illustrate in this review some applications of systems biology in the medical and biological areas. After a brief summary of time scales experienced by medical observations and of the general scheme of dynamic systems, we describe how some techniques underlying the complex systems theory can be applied to model medical issues in immunology, medical genetics, developmental morphogenesis, biochemistry, epidemiology, telemedecine and multiple platforms of expertises. In concluding, we will discuss the issue of "clinomics" coupling clinical and -omics data in a unique patient-specific file.
引用
收藏
页码：588 / 600
页数：13
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