Mutational analysis of BMP15 and GDF9 as candidate genes for premature ovarian failure

被引：77
|
作者：
Chand, Ashwini L.
Ponnampalam, Anna P.
Harris, Sarah E.
Winship, Ingrid M.
Shelling, Andrew N.
机构：
[1] Univ Auckland, Dept Obstet & Gynaecol, Fac Med & Hlth Sci, Auckland, New Zealand
[2] Univ Auckland, Dept Mol Med & Pathol, Fac Med & Hlth Sci, Auckland, New Zealand
来源：
FERTILITY AND STERILITY | 2006年 / 86卷 / 04期
关键词：
D O I：
10.1016/j.fertnstert.2006.02.107
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Mutational screening of the bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) genes in a population with premature ovarian failure (POF) identified no new mutations. However, three single nucleotide polymorphisms in the BMP15 gene, two in the 5' untranslated region (31T > G and 71C > G) and another in exon 1 (387G > A), were found to be common in both POF and control groups.
引用
收藏
页码：1009 / 1012
页数：4
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