Synthesis and Characterization of 4-Aryl-4H-chromenes from H-Cardanol

被引：0

作者：

Rao, Hulluru Surya Prakash ^{[1
]}

Kamalraj, Mani ^{[1
]}

机构：

[1] Pondicherry Univ, Dept Chem, Pondicherry 605014, India

来源：

NATURAL PRODUCT COMMUNICATIONS | 2014年 / 9卷 / 09期

关键词：

H-Cardanol; Nitroketene; Electrophilic substitution; 4-Aryl-4H-chromenes; NUT SHELL LIQUID; THROUGHPUT SCREENING ASSAY; APOPTOSIS INDUCERS; HTS ASSAY; DISCOVERY; SERIES; AGENTS; DERIVATIVES; POLYMERS; OIL;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We have synthesized and characterized a variety of fat-soluble, low-melting and medicinally useful 4-aryl-4H-chromenes from H-cardanol (side-chain perhydrogenated cardanol, 3-pentadecylphenol), a renewable and low-cost product from locally grown cashew nut trees (Anacardium occidentale L.). We incorporated H-cardanol into the aromatic rings of either 4H-chromene or phenol, or both. Substitution of C4SMe in N-methyl-4-(methylthio)-3-nitro-4Hchromene-2-amines with H-cardanol was regio-specific at the C6 position.

引用

页码：1333 / 1340

页数：8

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