Neurophysiological indices of free recall memory biases in major depression: The impact of stimulus arousal and valence

被引：3

作者：

Deldin, Patricia J. ^{[1
]}

Naidu, Shanthi K. ^{[2
]}

Shestyuk, Avgusta Y. ^{[3
]}

Casas, Brooks R. ^{[3
]}

机构：

[1] Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA

[2] Yale Univ, New Haven, CT USA

[3] Harvard Univ, Cambridge, MA 02138 USA

来源：

COGNITION & EMOTION | 2009年 / 23卷 / 05期

关键词：

Major depression; Memory; Emotion; ERP; Slow wave; P300; SLOW-WAVE; BRAIN POTENTIALS; WORKING-MEMORY; EMOTIONAL STIMULI; INFORMATION; SELF; ANXIETY; P300; MOOD; IMPAIRMENTS;

D O I：

10.1080/02699930802273573

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

This study examined differential impact of the valence and arousal characteristics of stimuli on memory biases and brain activity in major depressive disorder (MDD) and non-depressed control participants. P300 and slow wave (SW) components of the event-related brain potential (ERP) were recorded in 18 MDD and 18 control individuals during the encoding of positive and negative, high and low arousal words in a free recall task. Control participants demonstrated expected enhanced memory for positive stimuli that was accompanied by a corresponding increase in SW ERP components. These effects were not seen in the MDD participants. Rather, memory biases for negative information in MDD were only observed for low arousal words and were not reflected in ERP amplitudes. This study suggests that the inconsistency in the MDD memory bias literature may be related to the arousing nature of the stimuli incorporated in the study.

引用

页码：1002 / 1020

页数：19