Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection

被引:290
|
作者
Aravanis, Alexander M. [1 ]
Lee, Mark [1 ]
Klausner, Richard D. [1 ]
机构
[1] GRAIL, Menlo Pk, CA 94402 USA
关键词
SERVICES TASK-FORCE; PLASMA;
D O I
10.1016/j.cell.2017.01.030
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Curative therapies are most successful when cancer is diagnosed and treated at an early stage. We advocate that technological advances in next-generation sequencing of circulating, tumor-derived nucleic acids hold promise for addressing the challenge of developing safe and effective cancer screening tests.
引用
收藏
页码:571 / 574
页数:4
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