One-pot synthesis of hydrogen phosphonate derivatives of d4T and AZT

被引：29
|
作者：
Sun, XB
Kang, JX
Zhao, YF [1 ]
机构：
[1] Tsing Hua Univ, Key Lab Bioorgan Phosphorus Chem, Minist Educ, Dept Chem,Sch Life Sci & Engn, Beijing 100084, Peoples R China
[2] Zhengzhou Univ, Dept Chem, Henan 450052, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2002年 / 20期
关键词：
D O I：
10.1039/b207657h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and one-pot route for the synthesis of d4T or AZT hydrogen phosphonate derivatives via reaction of d4T or AZT with phosphorus trichloride, then alcoholysis and dealkylation in the presence of the corresponding alcohol is described.
引用
收藏
页码：2414 / 2415
页数：2
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