Toward performing transplantation in highly sensitized patients

被引:20
|
作者
Fuggle, SV [1 ]
Martin, S
机构
[1] Churchill Hosp, Oxford Transplant Ctr, Oxford OX3 7LJ, England
[2] Manchester Royal Infirm, Transplantat Lab, Manchester M13 9WL, Lancs, England
[3] UK Transplant Serv, Bristol BS10 5ND, Avon, England
[4] Univ Oxford, Nuffield Dept Surg, Oxford, England
关键词
renal transplantation; highly sensitized patients;
D O I
10.1097/01.tp.0000129257.34967.12
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Performing transplantation in highly sensitized patients represents a challenge for transplant units and organ exchange organizations. There are various approaches that can be adopted in order to transplant these patients, either through kidney exchange programs or by using desensitization protocols. In this article we discuss a number of these approaches, including the system currently used in the United Kingdom. The system encourages understanding of the patient's antibody profile and has resulted in a threefold increase in the number of highly sensitized patients undergoing transplantation.
引用
收藏
页码:186 / 189
页数:4
相关论文
共 50 条
  • [41] Detection of microchimerism in highly sensitized dialysis patients awaiting renal transplantation.
    Lui, SL
    Ramassar, V
    Holloran, PF
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1996, 7 (09): : A3211 - A3211
  • [42] HLA class II antibodies in highly sensitized patients awaiting renal transplantation
    Saidman, SL
    Fitzpatrick, D
    Mann, M
    Comerford, C
    Drew, L
    Marrari, M
    Duquesnoy, R
    [J]. HLA - GENETIC DIVERSITY OF HLA FUNCTIONAL AND MEDICAL IMPLICATION, PROCEEDINGS OF THE TWELFTH INTERNATIONAL HISTOCOMPATIBILITY WORKSHOP AND CONFERENCE (12TH IHWC), VOL II: CONFERENCE, 1997, : 545 - 547
  • [43] Kidney plus partial liver transplantation: A new option for highly sensitized patients?
    不详
    [J]. Nature Clinical Practice Nephrology, 2007, 3 (5): : 239 - 239
  • [44] Successful Renal Transplantation with Desensitization in Highly Sensitized Patients: A Single Center Experience
    Yoon, Hye Eun
    Hyoung, Bok Jin
    Hwang, Hyeon Seok
    Lee, So Young
    Jeon, Youn Joo
    Song, Joon Chang
    Oh, Eun-Jee
    Park, Sun Cheol
    Choi, Bum Soon
    Moon, In Sung
    Kim, Yong Soo
    Yang, Chul Woo
    [J]. JOURNAL OF KOREAN MEDICAL SCIENCE, 2009, 24 : S148 - S155
  • [45] Terminal Complement Inhibition for Highly Sensitized Patients Undergoing Heart Transplantation - Doable?
    Patel, J.
    Dilibero, D.
    Kittleson, M.
    Sana, S.
    Liou, F.
    Chang, D. H.
    Hage, A.
    Czer, L.
    Trento, A.
    Reinsmoen, N.
    Kobashigawa, J. A.
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2015, 34 (04): : S31 - S31
  • [46] KIDNEY TRANSPLANTATION IN HIGHLY SENSITIZED PATIENTS: SINGLE CENTRE EXPERIENCE IN NORTH GREECE
    Fylaktou, Asimina
    Chouridi, Maria
    Louka, Alexandra
    Myserli, Evangellia
    Issa, Marianthi
    Myserlis, Grigorios
    [J]. TISSUE ANTIGENS, 2015, 85 (05): : 414 - 414
  • [47] Management of highly sensitized patients in kidney transplantation: prospective single center strategy
    De Meyer, Martine
    Latinne, Dominique
    Lambert, Catherine
    De Pauw, Luc
    Buemi, Antoine
    Darius, Tom
    Goffin, Eric
    Kanaan, Nada
    Mourad, Michel
    [J]. TRANSPLANTATION, 2016, 100 (07) : S655 - S655
  • [48] HLA class II antibodies in highly sensitized patients awaiting renal transplantation
    Saidman, SL
    Fitzpatrick, D
    Mann, M
    Comerford, C
    Drew, L
    Marrari, M
    Duquesnoy, R
    [J]. HUMAN IMMUNOLOGY, 1996, 47 (1-2) : O709 - O709
  • [49] Stem cell transplantation for a highly sensitized patient
    Bartholomew, A
    Sher, D
    Sosler, S
    Stock, W
    Lazda, V
    Koshy, M
    vanBesien, K
    [J]. TRANSPLANTATION, 1999, 67 (07) : S14 - S14
  • [50] SUCCESSFUL RENAL TRANSPLANTATION IN HIGHLY SENSITIZED CHILDREN
    Loper, C.
    Pak, T.
    Rodig, N.
    Somers, M.
    [J]. PEDIATRIC TRANSPLANTATION, 2015, 19 : 145 - 145