What do hormones have to do with aging? What does aging have to do with hormones?

被引：11
|
作者：
Harman, SM [1 ]
机构：
[1] Kronos Longev Res Inst, Phoenix, AZ 85016 USA
来源：
STRATEGIES FOR ENGINEERED NEGLIGIBLE SENESCENCE: WHY GENUINE CONTROL OF AGING MAY BE FORESEEABLE | 2004年 / 1019卷
关键词：
hormones; aging; diet; cell; damage; oxidative stress;
D O I：
10.1196/annals.1297.051
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
It is clear that aging results in alterations of endocrine physiology, which in turn appear to contribute to development of the senescent phenotype. How the underlying basic aging process or processes cause the endocrine cell dysfunctions leading to hormone imbalance is far from clear, but oxidative alteration of cell membranes is an attractive candidate mechanism that might be susceptible to some degree of global remediation.
引用
收藏
页码：299 / 308
页数：10
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