In Vitro Expanded γδ T Cells Derived from Cord Blood Induce Potent and Specific Cytotoxicity Against Human Acute Myeloid Leukemia Cells

被引:0
|
作者
Cheung, Alice M. S. [1 ]
Tan, Kar Wai [2 ]
Guo, Dian Yan [2 ]
Goh, Su-Ann [1 ]
Lau, Amanda Sy [2 ]
Linn, Yeh Ching [3 ]
Hwang, William Y. K. [3 ]
Goh, Yeow Tee [3 ]
Li, Shang [1 ]
机构
[1] Duke NUS Med Sch, Canc & Stem Cell Biol, Singapore, Singapore
[2] Singapore Gen Hosp, Dept Clin Translat Res, Singapore, Singapore
[3] Singapore Gen Hosp, Dept Haematol, Singapore, Singapore
关键词
D O I
10.1182/blood.V128.22.2168.2168
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2168
引用
收藏
页数:5
相关论文
共 50 条
  • [21] Cytotoxicity of anti-CD64-ricin A chain immunotoxin against human acute myeloid leukemia cells in vitro and in SCID mice
    Zhong, RK
    Van De Winkel, JGJ
    Thepen, T
    Schultz, LD
    Ball, ED
    JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2001, 10 (01): : 95 - 105
  • [22] Human Umbilical Cord Blood-Derived Stromal Cells Are Superior to Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Inducing Myeloid Lineage Differentiation In Vitro
    Sun, Hao-Ping
    Zhang, Xi
    Chen, Xing-Hua
    Zhang, Cheng
    Gao, Lei
    Feng, Yi-Mei
    Peng, Xian-Gui
    Gao, Li
    STEM CELLS AND DEVELOPMENT, 2012, 21 (09) : 1429 - 1440
  • [23] Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells
    Tur, MK
    Huhn, M
    Thepen, T
    Stöcker, M
    Krohn, R
    Vogel, S
    Jost, E
    Osieka, R
    van de Winkel, JG
    Fischer, R
    Finnern, R
    Barth, S
    CANCER RESEARCH, 2003, 63 (23) : 8414 - 8419
  • [24] PROTEIN DISULPHIDE INHIBITORS INDUCE DIFFERENTIATION OF HUMAN ACUTE MYELOID LEUKEMIA CELLS
    Chlebowska, J.
    Firczuk, M.
    Furs, K.
    Muchowicz, A.
    Sadowski, R.
    Golab, J.
    Nowis, D.
    HAEMATOLOGICA, 2014, 99 : 558 - 558
  • [25] Dendritic cells from acute myeloid leukemia in complete remission pulsed with autologous leukemic cell lysates induce efficient leukemia-specific cytotoxicity.
    He, XP
    You, SG
    Bian, SG
    Li, M
    Ge, W
    Ma, S
    Zhao, RCH
    BLOOD, 2000, 96 (11) : 118A - 118A
  • [26] In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
    Montoya, Justin J.
    Turnidge, Megan A.
    Wai, Daniel H.
    Patel, Apurvi R.
    Lee, David W.
    Gokhale, Vijay
    Hurley, Laurence H.
    Arceci, Robert J.
    Wetmore, Cynthia
    Azorsa, David O.
    BMC CANCER, 2019, 19 (01)
  • [27] In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
    Justin J. Montoya
    Megan A. Turnidge
    Daniel H. Wai
    Apurvi R. Patel
    David W. Lee
    Vijay Gokhale
    Laurence H. Hurley
    Robert J. Arceci
    Cynthia Wetmore
    David O. Azorsa
    BMC Cancer, 19
  • [28] A new recombinant immunotoxin hscFv-ETA' demonstrates specific cytotoxicity against chronic myeloid leukemia cells in vitro
    Zhu, Xiaoying
    Tao, Kun
    Li, Yajuan
    Li, Shenfeng
    Zhang, Lijun
    Wang, Dong
    Zhong, Liang
    Feng, Wenli
    IMMUNOLOGY LETTERS, 2013, 154 (1-2) : 18 - 24
  • [29] Potent cytotoxicity against multiple myeloma and acute myeloid leukemia cells by a new histone deacetylase inhibitor ITF2357
    Rambaldi, A
    Mici, C
    Cuppini, L
    Domenghini, M
    Borleri, GM
    Barbui, AM
    Leoni, F
    Mascagni, P
    Salvi, A
    Golay, J
    Introna, M
    BLOOD, 2005, 106 (11) : 939A - 939A
  • [30] CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity
    Sauer, Tim
    Parikh, Kathan
    Sharma, Sandhya
    Omer, Bilal
    Gottschalk, Stephen
    Rooney, Cliona M.
    BLOOD, 2019, 134