Synthesis and Crystal Structure of Novel Derivatives of 1,5-Benzo[b]thiazepine

被引：0

作者：

Ye, Jiawei ^{[1
]}

Yang, Chun ^{[2
]}

Yang, Debao ^{[2
]}

Liu, Fangming ^{[1
,2
]}

机构：

[1] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830046, Peoples R China

[2] Hangzhou Normal Univ, Coll Mat & Chem Engn, Hangzhou 310036, Zhejiang, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 29卷 / 03期

关键词：

1,5-benzothiazepine; beta-lactam; crystallographic structure;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Eight title compounds were synthesized by the multi-step reaction using beta-dimethylamino-propiophenone hydrochloride as stating materials, followed by aldol condensation, cyclization with o-aminothiophenol, and [2+2] cycloaddition reaction with chloroacetyl chloride. The structures of these compounds were characterized by H-1 NMR, MS techniques and elemental analysis. Compound 4e was subjected to single crystal X-ray diffraction analysis to determine their structure.

引用

页码：414 / 419

页数：6