Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside

被引：90

作者：

Rowe-Rendleman, Cheryl L. ^{[1
]}

Durazo, Shelley A. ^{[2
]}

Kompella, Uday B. ^{[2
]}

Rittenhouse, Kay D. ^{[3
]}

Di Polo, Adriana ^{[4
]}

Weiner, Alan L. ^{[5
]}

Grossniklaus, Hans E. ^{[6
]}

Naash, Muna I. ^{[7
]}

Lewin, Alfred S. ^{[8
]}

Horsager, Alan ^{[9
]}

Edelhauser, Henry F. ^{[6
]}

机构：

[1] Omar Consulting Grp LLC, Princeton Jct, NJ USA

[2] Univ Colorado, Aurora, CO 80045 USA

[3] Pfizer Inc, San Diego, CA USA

[4] Univ Montreal, Montreal, PQ, Canada

[5] DrugDel Consulting LLC, Arlington, TX USA

[6] Emory Univ, Ctr Eye, Atlanta, GA 30322 USA

[7] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK USA

[8] Univ Florida, Gainesville, FL USA

[9] Univ So Calif, Inst Med Genet, Los Angeles, CA USA

来源：

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2014年 / 55卷 / 04期

关键词：

drug delivery; gene therapy; retina; nanoparticle; translational medicine; COMPACTED DNA-NANOPARTICLES; LEBER CONGENITAL AMAUROSIS; RETINAL GANGLION-CELLS; ADENOASSOCIATED VIRUS; DIPEPTIDE PRODRUGS; RPE65; MUTATIONS; VISUAL FUNCTION; THERAPY; MOUSE; PHARMACOKINETICS;

D O I：

10.1167/iovs.13-13707

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

[No abstract available]

引用

页码：2714 / 2730

页数：17

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