Facile and Convenient One-pot Synthesis of 1,1-Disubstituted Cyclopropanes in Water

被引：0

作者：

Liu Chun

Pan Wei ^{[1
]}

Yang Yang ^{[1
]}

Wang Ke-wei ^{[1
]}

Dong De-wen ^{[1
]}

机构：

[1] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China

来源：

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES | 2009年 / 25卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Cyclopropane; beta-Dicarbonyl compound; Tetrabutylammonium bromide; Water; DIELS-ALDER REACTIONS; ORGANIC-REACTIONS; AQUEOUS-MEDIA; DERIVATIVES; RING; CATALYSTS; PHASE; FOCUS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile and convenient one-pot synthesis method of substituted cyclopropanes in water has been developed. A series of 1, 1-disubstituted cyclopropanes 3 were synthesized from the reaction of beta-dicarbonyl Compounds 1 with 1,2-dibromoethane 2, in very high yields catalyzed by tetrabutylammonium bromide(TBAB) at 50 degrees C in the presence of K2CO3 in water. The catalyst TBAB in the aqueous phase can be reused after the separation of organic products.

引用

页码：37 / 39

页数：3

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