Facile and Convenient One-pot Synthesis of 1,1-Disubstituted Cyclopropanes in Water

被引：0
|
作者：
Liu Chun
Pan Wei [1 ]
Yang Yang [1 ]
Wang Ke-wei [1 ]
Dong De-wen [1 ]
机构：
[1] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China
来源：
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES | 2009年 / 25卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Cyclopropane; beta-Dicarbonyl compound; Tetrabutylammonium bromide; Water; DIELS-ALDER REACTIONS; ORGANIC-REACTIONS; AQUEOUS-MEDIA; DERIVATIVES; RING; CATALYSTS; PHASE; FOCUS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile and convenient one-pot synthesis method of substituted cyclopropanes in water has been developed. A series of 1, 1-disubstituted cyclopropanes 3 were synthesized from the reaction of beta-dicarbonyl Compounds 1 with 1,2-dibromoethane 2, in very high yields catalyzed by tetrabutylammonium bromide(TBAB) at 50 degrees C in the presence of K2CO3 in water. The catalyst TBAB in the aqueous phase can be reused after the separation of organic products.
引用
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页码：37 / 39
页数：3
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