Targeting WNT signaling in vivo via Tankyrase inhibition.

被引：0
|
作者：
Schatoff, Emma M. [1 ]
Leach, Benjamin I. [1 ]
Foronda, Miguel [1 ]
Zafra, Maria Paz [1 ]
Dow, Lukas [1 ]
机构：
[1] Weill Cornell Med, New York, NY USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 10期
关键词：
D O I：
10.1158/1538-7445.MOUSEMODELS17-B32
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B32
引用
收藏
页码：70 / 70
页数：1
相关论文
共 50 条
  • [31] TARGETING WNT SIGNALING TO REDUCE FIBROSIS
    Kuehlmann, Britta A.
    Bonham, Clark A.
    Gurtner, Geoffrey C.
    WOUND REPAIR AND REGENERATION, 2019, 27 (03) : A6 - A6
  • [32] Targeting Wnt Signaling in Endometrial Cancer
    Fatima, Iram
    Barman, Susmita
    Rai, Rajani
    Thiel, Kristina W.
    Chandra, Vishal
    CANCERS, 2021, 13 (10)
  • [33] Targeting WNT signaling in the treatment of osteoporosis
    Baron, Roland
    Gori, Francesca
    CURRENT OPINION IN PHARMACOLOGY, 2018, 40 : 134 - 141
  • [34] Direct targeting of β-catenin: Inhibition of protein-protein interactions for the inactivation of Wnt signaling
    Hahne, Gernot
    Grossmann, Tom N.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (14) : 4020 - 4026
  • [35] Inhibition of CML Stem Cell Growth By Targeting WNT Signaling Using a Porcupine Inhibitor
    Agarwal, Puneet
    Zhang, Bin
    Ho, YinWei
    Cook, Amy
    Li, Ling
    Wang, Youzhen
    McLaughlin, Margaret
    Bhatia, Ravi
    BLOOD, 2014, 124 (21)
  • [36] mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer
    Mashima, Tetsuo
    Taneda, Yoko
    Jang, Myung-Kyu
    Mizutani, Anna
    Muramatsu, Yukiko
    Yoshida, Haruka
    Sato, Ayana
    Tanaka, Noritaka
    Sugimoto, Yoshikazu
    Seimiya, Hiroyuki
    ONCOTARGET, 2017, 8 (29) : 47902 - 47915
  • [37] Control of Wnt/β-Catenin Signaling Pathway in Vivo via Light Responsive Capsules
    Anbrosone, Alfredo
    Marchesano, Valentina
    Carregal-Romero, Susana
    Intartaglia, Daniela
    Parak, Wolfgang J.
    Tortiglione, Claudia
    ACS NANO, 2016, 10 (04) : 4828 - 4834
  • [38] Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology
    Johannes, Jeffrey W.
    Almeida, Lynsie
    Barlaam, Bernard
    Boriack-Sjodin, P. Ann
    Casella, Robert
    Croft, Rosemary A.
    Dishington, Allan P.
    Gingipalli, Lakshmaiah
    Gu, Chungang
    Hawkins, Janet L.
    Holmes, Jane L.
    Howard, Tina
    Huang, Jian
    Ioannidis, Stephanos
    Kazmirski, Steven
    Lamb, Michelle L.
    McGuire, Thomas M.
    Moore, Jane E.
    Ogg, Derek
    Patel, Anil
    Pike, Kurt G.
    Pontz, Timothy
    Robb, Graeme R.
    Su, Nancy
    Wang, Haiyun
    Wu, Xiaoyun
    Zhang, Hai-Jun
    Zhang, Yue
    Zheng, Xiaolan
    Wang, Tao
    ACS MEDICINAL CHEMISTRY LETTERS, 2015, 6 (03): : 254 - 259
  • [39] Ubiquitin Ligase RNF146 Regulates Tankyrase and Axin to Promote Wnt Signaling
    Callow, Marinella G.
    Tran, Hoanh
    Phu, Lilian
    Lau, Ted
    Lee, James
    Sandoval, Wendy N.
    Liu, Peter S.
    Bheddah, Sheila
    Tao, Janet
    Lill, Jennie R.
    Hongo, Jo-Anne
    Davis, David
    Kirkpatrick, Donald S.
    Polakis, Paul
    Costa, Mike
    PLOS ONE, 2011, 6 (07):
  • [40] Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells
    Ma, Li
    Wang, Xiaolin
    Jia, Tao
    Wei, Wei
    Chua, Mei-Sze
    So, Samuel
    ONCOTARGET, 2015, 6 (28) : 25390 - 25401
12345