Human SCNT Gets a Boost from Histone Demethylation
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作者:
Deglincerti, Alessia
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Rockefeller Univ, Lab Stem Cell Biol & Mol Embryol, New York, NY 10065 USARockefeller Univ, Lab Stem Cell Biol & Mol Embryol, New York, NY 10065 USA
Deglincerti, Alessia
[1
]
Brivanlou, Ali H.
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Rockefeller Univ, Lab Stem Cell Biol & Mol Embryol, New York, NY 10065 USARockefeller Univ, Lab Stem Cell Biol & Mol Embryol, New York, NY 10065 USA
Brivanlou, Ali H.
[1
]
机构:
[1] Rockefeller Univ, Lab Stem Cell Biol & Mol Embryol, New York, NY 10065 USA
Human somatic cell nuclear transfer (SCNT) holds great potential in regenerative medicine; however, its applicability has been limited by great variability in reprogramming efficiencies. A new study in this issue of Cell Stem Cell reports a simple way to expand human SCNT to hard-to-reprogram oocytes (Chung et al., 2015).