Orally-active ice inhibitors for the treatment of inflammatory and autoimmune diseases.

被引：0
|
作者：
Randle, JCR [1 ]
机构：
[1] Vertex Pharmaceut Inc, Cambridge, MA 02319 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 228卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
200-MEDI
引用
收藏
页码：U944 / U944
页数：1
相关论文
共 50 条
  • [21] NOVEL 1,2-DIARYLCYCLOPENTENES ARE SELECTIVE, POTENT, AND ORALLY-ACTIVE CYCLOOXYGENASE INHIBITORS
    REITZ, DB
    LI, JJ
    NORTON, MB
    REINHARD, EJ
    HUANG, HC
    PENICK, MA
    COLLINS, JT
    GARLAND, DJ
    SEIBERT, K
    KOBOLDT, CM
    GREGORY, SA
    VEENHUIZEN, A
    ZHANG, Y
    ISAKSON, PC
    MEDICINAL CHEMISTRY RESEARCH, 1995, 5 (05) : 351 - 363
  • [22] Treatment of autoimmune liver diseases. Autoimmune hepatitis and primary sclerosing cholangitis
    Strassburg, C. P.
    Manns, M. P.
    INTERNIST, 2011, 52 (12): : 1394 - +
  • [23] Human dihydroorotate dehydrogenase inhibitors, a novel approach for the treatment of autoimmune and inflammatory diseases
    Leban, Johann
    Vitt, Daniel
    ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 2011, 61 (01): : 66 - 72
  • [24] Protein-kinase inhibitors: A new treatment pathway for autoimmune and inflammatory diseases?
    Hernandez-Florez, Diana
    Valor, Lara
    REUMATOLOGIA CLINICA, 2016, 12 (02): : 91 - 99
  • [25] NEW ORALLY-ACTIVE SERINE-PROTEASE INHIBITORS - STRUCTURAL REQUIREMENTS FOR THEIR GOOD ORAL ACTIVITY
    SENOKUCHI, K
    NAKAI, H
    NAKAYAMA, Y
    ODAGAKI, Y
    SAKAKI, K
    KATO, M
    MARUYAMA, T
    MIYAZAKI, T
    ITO, H
    KAMIYASU, K
    KIM, S
    KAWAMURA, M
    HAMANAKA, N
    JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (22) : 4508 - 4517
  • [26] Type I interferon in organ-targeted autoimmune and inflammatory diseases.
    Crow M.K.
    Arthritis Research & Therapy, 12 (Suppl 1): : S5
  • [27] DESIGN, SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF ORALLY-ACTIVE COAGULATION-FACTOR XA INHIBITORS
    NAGAHARA, T
    KATAKURA, S
    YOKOYAMA, Y
    KANAYA, N
    INAMURA, K
    KOMORIYA, S
    YAMADA, K
    YAMAGUCHI, H
    TANABE, K
    MORISHIMA, Y
    ISHIHARA, H
    HARA, T
    YAMAZAKI, K
    KUNITADA, S
    IWAMOTO, M
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1995, 30 : S139 - S143
  • [28] (1) Immunopharmacological Characterization of Potent, Selective and Orally Available RORγt Inhibitors for Treatment of Autoimmune Diseases
    Masuda, Junya
    Takeuchi, Takashi
    Tomizawa, Chinatsu
    Kawaji, Atsuko
    Asakura, Toshimichi
    Shimada, Shunsuke
    Negishi, Takaaki
    Kato, Yutaka
    Nakao, Kazunari
    Furusako, Shoji
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (02) : AB98 - AB98
  • [29] Xcellerate™ therapy:: A novel therapeutic strategy for the treatment of autoimmune diseases.
    Berenson, RJ
    Long, SA
    Kalamasz, D
    Ferrand, C
    Richards, M
    Khalili, J
    Frohlich, M
    Bonyhadi, ML
    BLOOD, 2003, 102 (11) : 239A - 239A
  • [30] SELECTIVE CYCLOOXYGENASE INHIBITORS - NOVEL 1,2-DIARYLCYCLOPENTENES ARE POTENT AND ORALLY-ACTIVE COX-2 INHIBITORS
    REITZ, DB
    LI, JJ
    NORTON, MB
    REINHARD, EJ
    COLLINS, JT
    ANDERSON, GD
    GREGORY, SA
    KOBOLDT, CM
    PERKINS, WE
    SEIBERT, K
    ISAKSON, PC
    JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (23) : 3878 - 3881
12345