Mimicking gangliosides by design: Mimics of GM1 headgroup

被引：20
|
作者：
Bernardi, A
Arosio, D
Sonnino, S
机构：
[1] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy
[2] Univ Milan, Dipartimento Chim & Biochim Med, LITA Segrate, Segrate, Italy
来源：
NEUROCHEMICAL RESEARCH | 2002年 / 27卷 / 7-8期
关键词：
Cholera toxin; ganglioside; ganglioside mimics; glycomimetics; molecular design;
D O I：
10.1023/A:1020251428217
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Detailed knowledge of the three-dimensional structure of ganglioside headgroups has allowed the successful design of structural and functional mimics of ganglioside GM1 oligosaccharide. Our recent work in this area is reviewed in this paper.
引用
收藏
页码：539 / 545
页数：7
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