Clonal relationship among Vibrio cholerae O1 El Tor strains isolated in Somalia

被引:8
|
作者
Scrascia, Maria [1 ]
Pugliese, Nicola [1 ]
Maimone, Francesco [1 ,2 ]
Mohamud, Kadigia A. [2 ]
Grimont, Patrick A. D. [3 ]
Materu, Sadiki F. [4 ]
Pazzani, Carlo [1 ]
机构
[1] Univ Bari, Dipartimento Genet & Microbiol, I-70126 Bari, Italy
[2] Univ Roma La Sapienza, Interuniv Res Ctr Sustainable Dev, I-00038 Rome, Italy
[3] Inst Pasteur, Unite Biodiversite Bacteries Pathogenes Emergente, F-75724 Paris 15, France
[4] AMREF, Nairobi, Kenya
关键词
Cholera; Clonal analysis; Antimicrobial resistance; Somalia; MOLECULAR EPIDEMIOLOGY; SPREAD; 1990S;
D O I
10.1016/j.ijmm.2008.07.003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
One hundred and three Vibrio cholerae 01 strains, selected to represent the cholera outbreaks which occurred in Somalia in 1998-1999, were characterized by random amplified polymorphic DNA patterns, ribotyping, and antimicrobial susceptibility. All strains showed a unique amplified DNA pattern and 2 closely related ribotypes (B5a and B8a), among which B5a was the more frequently identified. Ninety-one strains were resistant to ampicillin, chloramphenicol, spectinomycin, streptomycin, sulfamethoxazole, and trimethoprim, conferred, except for spectinomycin, by a conjugative plasmid IncC. These findings indicated that the group of strains active in Somalia in the late 1990s had a clonal origin. (C) 2008 Elsevier GmbH. All rights reserved.
引用
收藏
页码:203 / 207
页数:5
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