Synthesis of imidazo[4,5-b]pyridines from aminoimidazolecarbaldehydes

被引：16

作者：

Perandones, F

Soto, JL

机构：

[1] Depto. de Quim. Orgánica, Facultad de Química, Universidad Complutense

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 01期

关键词：

D O I：

10.1002/jhet.5570340118

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Amino-1,2-dimethylimidazole-5-carbaldehyde (1) and 5-amino-1-methylimidazole-4-carbaldehydes 3 were prepared by reduction of the corresponding aminoimidazolecarbonitriles 2 and 4. Condensation of 1 and 3 with carbonitriles, ketones and polyfunctional carbonyl compounds bearing the -CH2CO- moiety afforded to the imidazo[4,5-b]pyridine derivatives.

引用

页码：107 / 112

页数：6

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