Synthesis of imidazo[4,5-b]pyridines from aminoimidazolecarbaldehydes

被引：16
|
作者：
Perandones, F
Soto, JL
机构：
[1] Depto. de Quim. Orgánica, Facultad de Química, Universidad Complutense
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 01期
关键词：
D O I：
10.1002/jhet.5570340118
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4-Amino-1,2-dimethylimidazole-5-carbaldehyde (1) and 5-amino-1-methylimidazole-4-carbaldehydes 3 were prepared by reduction of the corresponding aminoimidazolecarbonitriles 2 and 4. Condensation of 1 and 3 with carbonitriles, ketones and polyfunctional carbonyl compounds bearing the -CH2CO- moiety afforded to the imidazo[4,5-b]pyridine derivatives.
引用
收藏
页码：107 / 112
页数：6
相关论文
共 50 条
  • [1] SYNTHESIS OF IMIDAZO[4,5-B] PYRIDINES
    HAYAKAWA, I
    YAMAZAKI, KI
    DOHMORI, R
    KOGA, N
    HETEROCYCLES, 1978, 10 : 241 - 245
  • [2] SYNTHESIS OF IMIDAZO[4,5-B]PYRIDINES AND [4,5-C]PYRIDINES
    MIDDLETON, RW
    WIBBERLEY, DG
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1980, 17 (08) : 1757 - 1760
  • [3] Annelated Aminoimidazoles in Synthesis of Imidazo[4,5-b]pyridines
    Shvydenko, Tetiana
    Nazarenko, Kostiantyn
    Shvydenko, Kostiantyn
    Rusanov, Eduard
    Tolmachev, Andrei
    Kostyuk, Aleksandr
    CHEMISTRYSELECT, 2019, 4 (29): : 8450 - 8452
  • [4] DERIVATIVES OF IMIDAZO[4,5-B]PYRIDINES AND OF IMIDAZO[4,5-C]PYRIDINES
    CLEVE, G
    GIBIAN, H
    HOYER, GA
    RAHTZ, D
    SCHRODER, E
    SCHULZ, G
    ANNALEN DER CHEMIE-JUSTUS LIEBIG, 1971, 747 (MAY): : 158 - &
  • [5] Efficient synthesis of substituted imidazo[4,5-b] pyridines
    Xing, Yuan-Yuan
    Liu, Chuanxiang
    Wu, Fanhong
    HETEROCYCLIC COMMUNICATIONS, 2013, 19 (05) : 327 - 330
  • [6] SYNTHESIS OF 2-ARYLSUBSTITUTED IMIDAZO[4,5-B]PYRIDINES AND IMIDAZO[4,5-C]PYRIDINES
    YUTILOV, YM
    SHCHERBINA, LI
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1987, (05): : 639 - 645
  • [7] SYNTHESIS OF POTENTIAL ANTICANCER AGENTS - IMIDAZO[4,5-C]PYRIDINES AND IMIDAZO[4,5-B]PYRIDINES
    TEMPLE, C
    ROSE, JD
    COMBER, RN
    RENER, GA
    JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (10) : 1746 - 1751
  • [8] SYNTHESIS OF POTENTIAL ANTICANCER AGENTS - IMIDAZO[4,5-C]PYRIDINES AND IMIDAZO[4,5-B]PYRIDINES
    TEMPLE, C
    ROSE, JD
    COMBER, RN
    RENER, GA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1987, 194 : 26 - MEDI
  • [9] Synthesis of 2-amino-imidazo[4,5-b]pyridines
    Rosenberg, Adam J.
    Williams, Theresa M.
    Jordan, Abraham J.
    Clark, Daniel A.
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2013, 11 (18) : 3064 - 3072
  • [10] IMIDAZO[4,5-C]-AND [4,5-B]PYRIDINES
    DENZEL, T
    HOHN, H
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1977, 14 (05) : 813 - 821
12345