Recent Progresses in Organic-Inorganic Nano Technological Platforms for Cancer Therapeutics

被引：12

作者：

Kumar, Sanjay ^{[1
,2
]}

Singhal, Anchal ^{[4
]}

Narang, Uma ^{[3
]}

Mishra, Sweta ^{[3
]}

Kumari, Pratibha ^{[2
]}

机构：

[1] Himachal Pradesh Univ, Dept Chem, Shimla, India

[2] Univ Delhi, Deshbandhu Coll, Dept Chem, New Delhi, India

[3] Univ Delhi, Dept Chem, New Delhi, India

[4] St Joseph Coll, Dept Chem, Bangalore, India

来源：

CURRENT MEDICINAL CHEMISTRY | 2020年 / 27卷 / 35期

关键词：

Cancer therapy; nanotechnology; organic-inorganic nanomaterials; cancer therapeutics; drug delivery; gene therapy; radiotherapy; MESOPOROUS SILICA NANOPARTICLES; SOLID LIPID NANOPARTICLES; ENTRAPPED GOLD NANOPARTICLES; IRON-OXIDE NANOPARTICLES; GRAPHENE QUANTUM DOTS; COATED MAGNETIC NANOPARTICLES; METAL-BASED NANOPARTICLES; TARGETED DRUG-DELIVERY; VITAMIN-E TPGS; IN-VIVO;

D O I：

10.2174/0929867326666181224143734

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nanotechnology offers promising tools in interdisciplinary research areas and getting an upsurge of interest in cancer therapeutics. Organic nanomaterials and inorganic nanomaterials bring revolutionary advancement in cancer eradication process. Oncology is achieving new heights under nano technological platform by expediting chemotherapy, radiotherapy, photo thermodynamic therapy, bio imaging and gene therapy. Various nanovectors have been developed for targeted therapy which acts as "Nano-bullets" for tumor cells selectively. Recently combinational therapies are catching more attention due to their enhanced effect leading towards the use of combined organic-inorganic nano platforms. The current review covers organic, inorganic and their hybrid nanomaterials for various therapeutic action. The technological aspect of this review emphasizes on the use of inorganic-organic hybrids and combinational therapies for better results and also explores the future opportunities in this field.

引用

页码：6015 / 6056

页数：42

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