Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: novel insights from a CRISPR/Cas9 adipocyte model

被引:0
|
作者
Teodoro, J. S. [1 ,2 ]
Silva, R. [1 ,2 ]
Rolo, A. P. [1 ,2 ]
Carvalho, R. A. [1 ]
Palmeira, C. M. [1 ,2 ]
机构
[1] Cnc Ibili, Coimbra, Portugal
[2] Univ Coimbra, Dept Life Sci, Coimbra, Portugal
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
W2-O2
引用
收藏
页码:51 / 51
页数:1
相关论文
共 50 条
  • [41] The bile acid receptor TGR5 inhibits platelet activation and thrombus formation
    Reusswig, Friedrich
    Reich, Maria
    Wienands, Leonard
    Herebian, Diran
    Keitel-Anselmino, Verena
    Elvers, Margitta
    PLATELETS, 2024, 35 (01)
  • [42] SECONDARY BILE ACIDS PROTECT AGAINST INTESTINAL INFLAMMATION VIA BILE ACID TGR5 RECEPTOR
    Sinha, Sidhartha R.
    Haileselassie, Yeneneh
    Linh Nguyen
    Tropini, Carolina
    Becker, Laren S.
    Sim, Davis
    Bittinger, Kyle
    Sonnenburg, Justin
    Habtezion, Aida
    GASTROENTEROLOGY, 2019, 156 (06) : S647 - S647
  • [43] TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload
    Bidault-Jourdainne, Valeska
    Merlen, Gregory
    Glenisson, Mathilde
    Doignon, Isabelle
    Garcin, Isabelle
    Pean, Noemie
    Boisgard, Raphael
    Ursic-Bedoya, Jose
    Serino, Matteo
    Ullmer, Christoph
    Humbert, Lydie
    Abdelrafee, Ahmed
    Golse, Nicolas
    Vibert, Eric
    Duclos-Vallee, Jean-Charles
    Rainteau, Dominique
    Tordjmann, Thierry
    JHEP REPORTS, 2021, 3 (02)
  • [44] Tongue bile acid receptor TGR5 is critically involved in preference for dietary lipids and obesity in mice: Role TGR5 in genetic polymorphism in human obese participants
    Sayed-Khan, Amira
    Bensalem, Adel
    Hichami, Aziz
    Oulamara, Hayet
    Khan, Naim Akhtar
    ACTA PHYSIOLOGICA, 2022, 236
  • [45] The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders
    Stepanov, Vanesa
    Stankov, Karmen
    Mikov, Momir
    JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2013, 33 (04) : 213 - 223
  • [46] Bile Acid Receptor TGR5 Agonism Enhances Vascular Endothelial Barrier Function
    Kida, Taiki
    Murata, Takahisa
    Hori, Masatoshi
    Ozaki, Hiroshi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013, 121 : 72P - 72P
  • [47] The Anticancer Mechanism of Bile Acid Receptor TGR5 in Mouse Models of Lung Cancer
    Liu, X.
    Qi, F.
    Sun, H.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 82 : 16 - 23
  • [48] The Bile Acid Receptor TGR5 (Gpbar-1) Acts as a Neurosteroid Receptor in Brain
    Keitel, Verena
    Goerg, Boris
    Bidmon, Hans J.
    Zemtsova, Irina
    Spomer, Lina
    Zilles, Karl
    Haeussinger, Dieter
    GLIA, 2010, 58 (15) : 1794 - 1805
  • [49] Taurochenodeoxycholic Acid Increases cAMP Content via Specially Interacting with Bile Acid Receptor TGR5
    Qi, Youchao
    Shi, Linkai
    Duan, Guozhen
    Ma, Yonggui
    Li, Peifeng
    MOLECULES, 2021, 26 (23):
  • [50] Changes in the Bile Acid Pool and Timing of Female Puberty: Potential Novel Role of Hypothalamic TGR5
    Vanden Brink, Heidi
    Vandeputte, Doris
    Brito, Ilana L.
    Ronnekleiv, Oline K.
    Roberson, Mark S.
    Lomniczi, Alejandro
    ENDOCRINOLOGY, 2024, 165 (09)