Efficient oxidative synthesis of 2-oxazolines

被引：85
|
作者：
Schwekendiek, Kirsten [1 ]
Glorius, Frank [1 ]
机构：
[1] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany
来源：
SYNTHESIS-STUTTGART | 2006年 / 18期
关键词：
amino alcohols; oxidative coupling; oxazolines; oxazolidines; N-bromosuccinimide;
D O I：
10.1055/s-2006-950198
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New methodology for the synthesis of variously substituted 2-oxazolines and one dihydrooxazine using aldehydes, amino alcohols, and N-bromosuccinimide as an oxidizing agent is described. This one-pot synthesis is characterized by mild reaction conditions, broad scope, high yields, and its preparative simplicity.
引用
收藏
页码：2996 / 3002
页数：7
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