Efficient oxidative synthesis of 2-oxazolines

被引：85
|
作者：
Schwekendiek, Kirsten [1 ]
Glorius, Frank [1 ]
机构：
[1] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany
来源：
SYNTHESIS-STUTTGART | 2006年 / 18期
关键词：
amino alcohols; oxidative coupling; oxazolines; oxazolidines; N-bromosuccinimide;
D O I：
10.1055/s-2006-950198
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New methodology for the synthesis of variously substituted 2-oxazolines and one dihydrooxazine using aldehydes, amino alcohols, and N-bromosuccinimide as an oxidizing agent is described. This one-pot synthesis is characterized by mild reaction conditions, broad scope, high yields, and its preparative simplicity.
引用
收藏
页码：2996 / 3002
页数：7
相关论文
共 50 条
  • [1] Synthesis of 2-oxazolines as efficient reagents in organic synthesis and monomers for macromolecular chemistry
    Kronek, J
    Luston, J
    Bohme, F
    CHEMICKE LISTY, 1998, 92 (03): : 175 - 185
  • [2] A novel method for the synthesis of 2-oxazolines
    Jadhav, Krishna A.
    Bhosle, Siddhanath D.
    V. Itage, Shivanand
    Bhosale, Rajesh S.
    Eppa, Gyanchander
    Yadav, Jhillu Singh
    TETRAHEDRON LETTERS, 2022, 106
  • [3] ASYMMETRIC-SYNTHESIS OF GLYCIDIC 2-OXAZOLINES
    LIDDELL, R
    WHITELEY, C
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1983, (24) : 1535 - 1537
  • [4] An efficient synthesis of uracil derivatives from 2-alkyl-Δ2-oxazolines and nitriles
    Fustero, Santos
    Sanz-Cervera, Juan F.
    Merida, Salvador
    Roman, Raquel
    Villanova, Salvador
    Ramirez de Arellano, Carmen
    JOURNAL OF FLUORINE CHEMISTRY, 2008, 129 (09) : 836 - 847
  • [5] ELECTROREDUCTION OF 2-OXAZOLINES
    RYAN, CM
    KARIVMILLER, E
    TETRAHEDRON, 1988, 44 (22) : 6807 - 6810
  • [6] POLYMERIZATION OF 2-OXAZOLINES
    SEELIGER, W
    THIER, W
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1966, 5 (06) : 612 - &
  • [7] Synthesis and characterization of block copolymers from 2-oxazolines
    Marjorie Contreras, Maria
    Mattea, Carlos
    Carlos Rueda, Juan
    Stapf, Siegfried
    Bajd, Franci
    DESIGNED MONOMERS AND POLYMERS, 2015, 18 (02) : 170 - 179
  • [8] Synthesis of 2-oxazolines mediated by N,N′-diisopropylcarbodiimide
    Crosignani, S
    Young, AC
    Linclau, B
    TETRAHEDRON LETTERS, 2004, 45 (52) : 9611 - 9615
  • [9] Synthesis of a new class of 2-oxazolines and 2-thiazolines
    Padmaja, A.
    Payani, T.
    Mahesh, K.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2008, 47 (11): : 1713 - 1725
  • [10] Synthesis of 2-Oxazolines by in Situ Desilylation and Cyclodehydration of β-Hydroxyamides
    Brandstaetter, Marco
    Roth, Fabian
    Luedtke, Nathan W.
    JOURNAL OF ORGANIC CHEMISTRY, 2015, 80 (01): : 40 - 51
12345