Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in nonobese adolescents and women

被引：7

作者：

Ibanez, Lourdes ^{[1
]}

de Zegher, Francis

机构：

[1] Univ Barcelona, Hosp St Joan Deu, Endocrinol Unit, Barcelona, Spain

[2] Katholieke Univ Leuven, Dept Woman & Child, Louvain, Belgium

来源：

FERTILITY AND STERILITY | 2006年 / 86卷

关键词：

body composition; hyperinsulinemic hyperandrogenism; hyperinsulinemia;

D O I：

10.1016/j.fertnstert.2006.03.006

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Hyperinsulinemic hyperandrogenism is the core of polycystic ovary syndrome (PCOS), and accordingly low-dose flutamide-metformin proved so far to be a most effective approach to normalize the broad spectrum of PCOS anomalies in nonobese adolescents and young women. For safety reasons, it is wise to combine flutamide-metformin with a contraceptive, for example, an oral or transdermal estroprogestagen.

引用

页码：S24 / S25

页数：2

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