Proteomic signals in simple transcriptional cascades

被引：2

作者：

Carstea, A. S. ^{[1
]}

Ramani, A. ^{[2
]}

Tamizhmani, K. M. ^{[3
]}

Grammaticos, B. ^{[4
]}

机构：

[1] Inst Phys & Nucl Engn, Dept Theoret Phys, Bucharest 077125, Romania

[2] Ecole Polytech, CNRS, Ctr Phys Theor, F-91128 Palaiseau, France

[3] Pondicherry Univ, Dept Math, Kalapet 605014, Puducherry, India

[4] Univ Paris 11, IMNC, CNRS, UMR 8165, F-91406 Orsay, France

来源：

CHAOS SOLITONS & FRACTALS | 2009年 / 41卷 / 04期

关键词：

GENETIC TOGGLE SWITCH; ESCHERICHIA-COLI; EXPRESSION; BACTERIA; NETWORKS; MOTIFS; SYSTEM;

D O I：

10.1016/j.chaos.2008.07.030

中图分类号：

O1 [数学];

学科分类号：

0701 ; 070101 ;

摘要：

A transcriptional gene network cascade with activation or repression coupling is analysed. For different promoter activity functions and different degradation rate of transcription factors we show that a proteomic signal is propagating along the cascade in the form of a kink wave, It represents the time evolution of transcription factor distribution showing a successive gene expression along the cascade. Biological implications are discussed. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1823 / 1827

页数：5

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