Mycobacterium tuberculosis complex and mycobacterial heat shock proteins in lymph node tissue from patients with pulmonary sarcoidosis

被引:72
|
作者
Dubaniewicz, Anna
Dubaniewicz-Wybieralska, Miroslawa
Sternau, Adam
Zwolska, Zofia
Izycka-Swieszewska, Ewa
Augustynowicz-Kopec, Ewa
Skokowski, Jaroslaw
Singh, Mahavir
Zimnoch, Lech
机构
[1] Med Univ Gdansk, Dept Pathophysiol, PL-80211 Gdansk, Poland
[2] Med Univ Gdansk, Dept Radiol, PL-80211 Gdansk, Poland
[3] Med Univ Gdansk, Dept Thorac Surg, PL-80211 Gdansk, Poland
[4] Natl Inst TB & Lung Dis, Warsaw, Poland
[5] Med Univ Gdansk, Dept Pathomorphol, PL-80211 Gdansk, Poland
[6] Med Univ Gdansk, Dept Surg Oncol, PL-80211 Gdansk, Poland
[7] LIONEX Diagnost & Therapeut GmbH, Braunschweig, Germany
[8] GBF, Braunschweig, Germany
[9] Med Univ Bialystok, Dept Med Pathomorphol, Bialystok, Poland
关键词
D O I
10.1128/JCM.01433-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We demonstrated that not whole Mycobacterium tuberculosis but its particular antigens, hsp70(Mtb), hsp65(Mtb), and bsp16(Mtb), are present in lymph node tissues of patients with sarcoidosis (SA). hsp16(Mtb), occurs in the early stage of SA, whereas hsp70(Mtb) occurs in stage II of SA. hsp65(Mtb) is highly expressed in the capillary vessels in lymph node tissues in patients with SA.
引用
收藏
页码:3448 / 3451
页数:4
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