Epidermolysis bullosa pruriginosa showing good response to low-dose thalidomide - a report of two cases

被引：10
|
作者：
Ranugha, P. S. S. [1 ]
Mohanan, S. [1 ]
Chandrashekar, L. [1 ]
Basu, D. [1 ]
Thappa, D. M. [1 ]
Rajesh, N. G. [1 ]
机构：
[1] JIPMER, Pondicherry 605006, India
来源：
DERMATOLOGIC THERAPY | 2014年 / 27卷 / 01期
关键词：
epidermolysis bullosa pruriginosa; thalidomide; FEATURES;
D O I：
10.1111/dth.12047
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Epidermolysis bullosa pruriginosa is a rare distinctive variant of dystrophic epidermolysis bullosa characterized by intense pruritus, lichenified plaques in linear distribution, and anonychia. It is a difficult condition to treat and causes a great deal of distress. The present authors report two cases showing good response to low-dose thalidomide, with clinical and symptomatic improvement. The exact mechanism of action is not yet clear.
引用
收藏
页码：60 / 63
页数：4
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