Pseudomonas aeruginosa renews its virulence factors

被引：43
|
作者：
Huber, Philippe [1 ,2 ,3 ,4 ]
Basso, Pauline [1 ,2 ,3 ,4 ]
Reboud, Emeline [1 ,2 ,3 ,4 ]
Attree, Ina [1 ,2 ,3 ,4 ]
机构：
[1] Univ Grenoble Alpes, F-38000 Grenoble, France
[2] CNRS, ERL5261, F-38000 Grenoble, France
[3] CEA, BIG BCI, F-38000 Grenoble, France
[4] INSERM, U1036, F-38000 Grenoble, France
来源：
ENVIRONMENTAL MICROBIOLOGY REPORTS | 2016年 / 8卷 / 05期
关键词：
RESPIRATORY EPITHELIAL-CELLS; ALKALINE PROTEASE; IV PILINS; D-ARAF; ELASTASE; GLYCOSYLATION; SECRETION; MOTILITY; STRAIN; PA7;
D O I：
10.1111/1758-2229.12443
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Highly divergent strains of the major human opportunistic pathogen Pseudomonas aeruginosa have been isolated around the world by different research laboratories. They came from patients with various types of infectious diseases or from the environment. These strains are devoid of the major virulence factor used by classical strains, the Type III secretion system, but possess additional putative virulence factors, including a novel two-partner secretion system, ExlBA, responsible for the hypervirulent behavior of some clinical isolates. Here, we review the genetic and phenotypic characteristics of these recently-discovered P. aeruginosa outliers.
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页码：564 / 571
页数：8
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