Catalytic enantioselective conjugate addition of fluorobis(phenylsulfonyl)methane to enals: synthesis of chiral monofluoromethyl compounds

被引：68
|
作者：
Zhang, Shilei [1 ]
Zhang, Yinan [1 ]
Ji, Yafei [1 ]
Li, Hao [1 ]
Wang, Wei [1 ]
机构：
[1] Univ New Mexico, Dept Chem & Chem Engn, Albuquerque, NM 87131 USA
来源：
CHEMICAL COMMUNICATIONS | 2009年 / 32期
关键词：
MICHAEL ADDITION; RECEPTORS; CHEMISTRY; FLUORINE; MALONATE; BINDING;
D O I：
10.1039/b907399j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new highly catalytic enantioselective Michael addition of fluorobis(phenylsulfonyl)methane to alpha,beta-unsaturated aldehydes has been developed for the preparation of chiral monofluoromethyl compounds under mild reaction conditions.
引用
收藏
页码：4886 / 4888
页数：3
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