Differential in vitro expression of the brkA gene in Bordetella pertussis an Bordetella parapertussis clinical isolates

被引：9
|
作者：
Stefanelli, Paola
Sanguinetti, Maurizio
Fazio, Cecilia
Posteraro, Brunella
Fadda, Giovanni
Mastrantonio, Paola
机构：
[1] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, I-00161 Rome, Italy
[2] Univ Cattolica Sacro Cuore, Inst Microbiol, Rome, Italy
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2006年 / 44卷 / 09期
关键词：
D O I：
10.1128/JCM.00247-06
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In this study, we set up a real-time reverse transcriptase PCR assay to measure the relative amounts of brkA transcripts in 50 Bordetella isolates. The results suggested that brkA expression is strain dependent and its level may play a role in determining the serum resistance or susceptibility phenotype. Pertussis immunocompetent sera were unable to kill Bordetella parapertussis via complement deposition.
引用
收藏
页码：3397 / 3400
页数：4
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