The present experiment was conducted to observe the beneficial effect of dietary supplementation of sodium salt of isobutric acid in low protein and urea containing wheat strafe (WS) based diets, Eighteen crossbred growing calves, divided into 3 similar groups, were fed a basal diet consisting of wheat straw, concentrate mixture and green oat fodder in 40:40:20 proportion (T-1), basal diet + isobutyric acid (BCFA) @0.75% of basal diet (T-2) and basal diet + BCFA + Urea to replace 1/3rd of dietary nitrogen (T,) for 120 days. The average DMI (kg/100kg BW) was higher in T-3 (2.55) as compared to T-1 (1.95) and T-2 (1.95). The dietary supplementation of isobutyric acid improved the DM, OM and CF digestibilities by 8.6, 8,0 and 13.2% over T. The DCP content of experimental rations was similar in all the groups. However the DCP intake (g/day and g/kg W-0.75) was higher in T3 (304.55 and 6,70) as compared to T1 (2 17,90 and 5,01) and 12 (226,94 and 5.52). Similarly TDN intake (g/day and g/kg W-0.75) was also higher (P<0.05) in T-3 (2.63 and 58.20) as compared to T-1 (1.80 and 41.80) and T-2 (1.90 and 43.95). However, the TDN content of both the BCFA supplemented rations was significantly (P<0.01) higher (64.35 and 63.23%) as compared to T-1 (59.60). The total gain in live weight in T-2 and T-3 was higher by 15.94 and 30.02%, respectively, over T-1. The average daily gain and efficiency of feed conversion were also higher in BCFA supplemented groups i.e.. T-2 and T-3 calves by 13.38 and 26.71 and 12.48 and 22.16%, respectively. over T-1. The dietary supplementation of isobutyric acid improved the digestibility of nutrients and growth performance of calves.