Cutaneous melanoma remains a challenge despite increased levels of awareness, education and targeted health policies. Worldwide incidence rates for cutaneous melanoma have risen faster than those for any other malignancy in Caucasian populations over the last 30 years. Despite improving survival rates (defined as the ratio of those who survive the disease against incidence) over this period, mortality rates, generally, have continued to climb. Mortality from melanoma is greater than that caused by all other types of skin cancer, especially in men. In Britain the percentage of increase in the male age standardised mortality rate surpassed that of all other malignancies assessed (1993-2002) by Cancer Research UK. A literature-based study was conducted with review of publications identified through Medline and EMBase, 1980-December 2005, databases. We present a review of the current literature on incidence, mortality and survival rates of melanoma including a discussion on the aetiological factors, behaviour modification associated with public education campaigns and recent health policies and the effect these are having on melanoma figures. It is likely that any fall in mortality rates from melanoma in the near future will be secondary to early detection. Changes resulting from primary prevention are unlikely to be noticeable for several decades. (c) 2006 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
机构:
Royal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North Ireland
Hunter, H. L.
Dolan, O. M.
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Royal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North IrelandRoyal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North Ireland
Dolan, O. M.
McMullen, E.
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Ulster Hosp Dundonald, Belfast, Antrim, North IrelandRoyal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North Ireland
McMullen, E.
Donnelly, D.
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Northern Ireland Canc Registry, Belfast, Antrim, North IrelandRoyal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North Ireland
Donnelly, D.
Gavin, A.
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Northern Ireland Canc Registry, Belfast, Antrim, North IrelandRoyal Victoria Hosp, Dept Dermatol, Belfast BT12 6BA, Antrim, North Ireland
机构:
Louisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Wu, Xiao-Cheng
Eide, Melody J.
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机构:
Henry Ford Hosp, Dept Dermatol, Detroit, MI 48202 USA
Henry Ford Hosp, Dept Biostat & Res Epidemiol, Detroit, MI 48202 USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Eide, Melody J.
King, Jessica
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机构:
Ctr Dis Control & Prevent, Div Canc Prevent & Control, Atlanta, GA USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
King, Jessica
Saraiya, Mona
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Ctr Dis Control & Prevent, Div Canc Prevent & Control, Atlanta, GA USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Saraiya, Mona
Huang, Youjie
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Florida Dept Hlth, Bur Epidemiol, Tallahassee, FL USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Huang, Youjie
Wiggins, Charles
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Univ New Mexico, New Mexico Tumor Registry, Albuquerque, NM 87131 USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Wiggins, Charles
Barnholtz-Sloan, Jill S.
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Case Western Reserve Univ, Sch Med, Case Comprehens Canc Ctr, Cleveland, OH USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Barnholtz-Sloan, Jill S.
Martin, Nicolle
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Morehouse Sch Med, Dept Community Hlth & Prevent Med, Atlanta, GA 30310 USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Martin, Nicolle
Cokkinides, Vilma
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机构:
Amer Canc Soc, Atlanta, GA 30329 USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Cokkinides, Vilma
Miller, Jacqueline
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Ctr Dis Control & Prevent, Div Canc Prevent & Control, Atlanta, GA USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Miller, Jacqueline
Patel, Pragna
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机构:
Ctr Dis Control & Prevent, Div HIV AIDS Prevent, Atlanta, GA USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Patel, Pragna
Ekwueme, Donatus U.
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Ctr Dis Control & Prevent, Div Canc Prevent & Control, Atlanta, GA USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
Ekwueme, Donatus U.
Kim, Julian
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机构:
Univ Hosp Cleveland, Dept Surg, Case Med Ctr, Div Surg Oncol, Cleveland, OH 44106 USALouisiana State Univ, Hlth Sci Ctr, Sch Publ Hlth, Louisiana Tumor Registry,Epidemiol Program, New Orleans, LA USA
机构:
Karolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Karolinska Univ Hosp, Theme Canc, Stockholm, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Helgadottir, Hildur
Mikiver, Rasmus
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机构:
Linkoping Univ, Reg Canc Ctr Southeast Sweden, Linkoping, Sweden
Linkoping Univ, Dept Clin & Expt Med, Linkoping, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Mikiver, Rasmus
Schultz, Karina
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机构:
Karolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Karolinska Univ Hosp, Theme Canc, Stockholm, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Schultz, Karina
Nielsen, Kari
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机构:
Skane Univ Hosp, Dept Dermatol, Lund, Sweden
Lund Univ, Dept Clin Sci, Skin Canc Res Grp, Dermatol, Lund, Sweden
Helsingborg Hosp, Dept Dermatol, Helsingborg, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Nielsen, Kari
Portelli, Francesca
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机构:
Karolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Karolinska Univ Hosp, Dept Clin Pathol & Canc Diagnost, Stockholm, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Portelli, Francesca
Lapins, Jan
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机构:
Karolinska Univ Hosp, Dept Dermatol, Stockholm, Sweden
Karolinska Inst, Dept Med Huddinge, Dermatol & Venereol Unit, Stockholm, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Lapins, Jan
Puig, Susana
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机构:
Univ Barcelona, Hosp Clin Barcelona, Inst Invest Biomed August Pi i Sunyer, Dermatol Dept,Melanoma Unit, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Raras, Barcelona, SpainKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
Puig, Susana
Isaksson, Karolin
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机构:
Lund Univ, Dept Clin Sci, Surg, Lund, Sweden
Kristianstad Hosp, Dept Surg, Kristianstad, SwedenKarolinska Inst, Dept Oncol & Pathol, Stockholm, S-17176, Sweden
机构:
Newcastle Gen Hosp, Dept Reg Med Phys, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, EnglandNewcastle Gen Hosp, Dept Reg Med Phys, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England