Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase (vol 55, pg 2481, 2012)

被引:1
|
作者
Sofia, Michael J.
Chang, Wonsuk
Furman, Phillip A.
Mosley, Ralph T.
Ross, Bruce S.
机构
关键词
D O I
10.1021/acs.jmedchem.7b00427
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:3219 / 3219
页数:1
相关论文
共 50 条
  • [21] Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity
    Shirota, Y
    Luo, H
    Qin, WP
    Kaneko, S
    Yamashita, T
    Kobayashi, K
    Murakami, S
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (13) : 11149 - 11155
  • [22] Biochemical and structural analysis of the NS5B RNA-dependent RNA polymerase of the hepatitis C virus
    Lohmann, V
    Roos, A
    Körner, F
    Koch, JO
    Bartenschlager, R
    [J]. JOURNAL OF VIRAL HEPATITIS, 2000, 7 (03) : 167 - 174
  • [23] Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase
    Kukolj, G
    McGibbon, GA
    McKercher, G
    Marquis, M
    Lefèbvre, S
    Thauvette, L
    Gauthier, J
    Goulet, S
    Poupart, MA
    Beaulieu, PL
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (47) : 39260 - 39267
  • [24] Resistance to HCV nucleoside analogue inhibitors of hepatitis C virus RNA-dependent RNA polymerase
    Najera, Isabel
    [J]. CURRENT OPINION IN VIROLOGY, 2013, 3 (05) : 508 - 513
  • [25] The synthesis and biological activity of some nucleoside analog inhibitors of Hepatitis C virus RNA polymerase (NS5B)
    MacCoss, Malcolm
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237 : 717 - 717
  • [26] Identification of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors from high throughput screening
    Lee, MK
    Kim, HS
    Choi, JR
    Kim, YZ
    Cho, WY
    Cho, YG
    Kim, GW
    Kim, TG
    Hwang, JT
    Cho, DG
    Roh, KY
    Yoon, HS
    Lee, HS
    Kim, HJ
    Kim, J
    [J]. ANTIVIRAL RESEARCH, 2003, 57 (03) : A89 - A89
  • [27] Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B
    Schoenfeld, Ryan C.
    Bourdet, David L.
    Brameld, Ken A.
    Chin, Elbert
    de Vicente, Javier
    Fung, Amy
    Harris, Seth F.
    Lee, Eun K.
    Le Pogam, Sophie
    Leveque, Vincent
    Li, Jim
    Lui, Alfred S. -T.
    Najera, Isabel
    Rajyaguru, Sonal
    Sangi, Michael
    Steiner, Sandra
    Talamas, Francisco X.
    Taygerly, Joshua P.
    Zhao, Junping
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (20) : 8163 - 8182
  • [28] Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase
    Ding, Y
    Girardet, JL
    Smith, KL
    Larson, G
    Prigaro, B
    Lai, VCH
    Zhong, WD
    Wu, JZ
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (03) : 675 - 678
  • [29] The hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations
    Alaoui-Ismaili, MH
    Hamel, M
    L'Heureux, L
    Nicolas, O
    Bilimoria, D
    Labonté, P
    Mounir, S
    Rando, RF
    [J]. JOURNAL OF HUMAN VIROLOGY, 2000, 3 (06) : 306 - 316
  • [30] De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus
    Luo, GX
    Hamatake, RK
    Mathis, DM
    Racela, J
    Rigat, KL
    Lemm, J
    Colonno, RJ
    [J]. JOURNAL OF VIROLOGY, 2000, 74 (02) : 851 - 863