First synthesis of tert-butyl-substituted [1,2,4]triazino[5,6-b]indole-3-thiols and indolo[2,3-b]quinoxalines

被引：2

作者：

Lv, Mingyue ^{[1
]}

Zheng, Hongmei ^{[1
]}

Li, Yang ^{[1
]}

Gao, Wentao ^{[1
]}

机构：

[1] Bohai Univ, Inst Superfine Chem, Jinzhou 121000, Peoples R China

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2015年 / 41卷 / 10期

关键词：

tert-Butyl group; 1,2,4] Triazino[5,6-b]indole; Indolo [2,3-b]quinoxaline; Isatin; Benzene-1,2-diamine; Thiosemicarbazide; BIOLOGICAL EVALUATION; ANTIMALARIAL ACTIVITY; DERIVATIVES; SPECTRA;

D O I：

10.1007/s11164-014-1788-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this investigation, the first introduction of a tert-butyl group into [1,2,4]triazino[5,6-b]indole and indolo[2,3-b]quinoxaline systems, leading to a series of structurally novel 8-(t-butyl)-5H-[1,2,4]triazino[5,6-b]indole-3-thiol and 9-(t-butyl)-6H-indolo[2,3-b]quinoxaline derivatives, has been achieved by condensation of tert-butyl-substituted isatins with benzene-1,2-diamine or thiosemicarbazide. The molecular structures of these newly synthesized compounds were elucidated on the basis of elemental analysis and spectral data.

引用

页码：6927 / 6939

页数：13

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