Development of self-anchoring bone implants .2. Bone-implant interface characteristics in vitro

被引:0
|
作者
Vemuganti, A
Siegler, S
Abusafieh, A
Kalidindi, S
机构
[1] DREXEL UNIV,DEPT MAT ENGN,PHILADELPHIA,PA 19104
[2] DREXEL UNIV,DEPT MECH ENGN & MECH,PHILADELPHIA,PA 19104
[3] DREXEL UNIV,INST BIOMED ENGN & SCI,PHILADELPHIA,PA 19104
来源
关键词
self-anchoring; bone implants; fixation characteristics; push-out mechanical tests;
D O I
10.1002/(SICI)1097-4636(199724)38:4<328::AID-JBM4>3.0.CO;2-Q
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A new swelling copolymeric material suitable for self-anchoring bone implants was introduced in part I of this two-part article. The main goal in the second part of the study was to investigate the in vitro fixation characteristics of these novel implants in bone using push-out mechanical testing. Specifically, we examined the various factors that influence the in vitro fixation levels achieved by these anchors and identified a range of copolymer compositions that provide good fixation characteristics for these implants. The factors studied included the copolymer composition, presence of AS-4 carbon fiber reinforcement, and the time of implantation (in an environment of saline solution). The push-out tests were conducted on smooth cylindrical plugs of the swelling materials that were implanted in bovine cortical bone. The bone-implant system was then immersed in saline solution for various periods of time ranging from 1 to 28 days prior to push-out testing. The refixation characteristics of the implants were also investigated in this study by performing repeated push-out tests on a single implant without completely dislodging the implant from the bone. Holding strengths comparable and often exceeding many current orthopedic fixation techniques were obtained (push-out load exceeding 1000 N and shear strength exceeding 7 MPa) with the implant having 80/20 to 70/30 methyl methacrylate/acrylic acid ratios. Furthermore, more than 80% of the ultimate holding strength could be achieved within 7 days of implantation at ambient temperature for the 80/20 composite implants. Excellent refixation properties were demonstrated in which the implant regained its full holding strength in the bone immediately after an initial failure. These results indicate great potential for the possible use of these implants for orthopedic applications such as suture anchoring and internal fracture fixations. (C) 1997 John Wiley & Sons, Inc.
引用
收藏
页码:328 / 336
页数:9
相关论文
共 50 条
  • [41] Optimization of stress distribution of bone-implant interface (BII)
    Zhang, Chunyu
    Zeng, Chunyu
    Wang, Zhefu
    Zeng, Ting
    Wang, Yuehong
    BIOMATERIALS ADVANCES, 2023, 147
  • [42] Bone-implant contact of surface-modified titanium implants
    Kim, Nam Gyu
    Park, Il Song
    Yi, Ho Keun
    Ahn, Seung Geun
    Song, Kwang Yeob
    Bae, Tae Sung
    Lee, Min Ho
    MULTI-FUNCTIONAL MATERIALS AND STRUCTURES, PTS 1 AND 2, 2008, 47-50 : 1294 - 1297
  • [43] Development of thermal measurement system for investigating temperature distribution at bone-implant interface
    Xu, W
    Hughes, S
    ISMTII'2001: PROCEEDINGS OF THE FIFTH INTERNATIONAL SYMPOSIUM ON MEASUREMENT TECHNOLOGY AND INTELLIGENT INSTRUMENTS, 2001, : 137 - 143
  • [44] Bone-implant degradation and mechanical response of bone surrounding Mg-alloy implants
    Meischel, Martin
    Hoermann, Daniel
    Draxler, Johannes
    Tschegg, Elmar K.
    Eichler, Johannes
    Prohaska, Thomas
    Stanzl-Tscheg, Stefanie E.
    JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2017, 71 : 307 - 313
  • [45] A MODEL FOR THE IMPLANT-BONE INTERFACE CHARACTERISTICS OF POROUS DENTAL IMPLANTS
    COOK, SD
    KLAWITTER, JJ
    WEINSTEIN, AM
    JOURNAL OF DENTAL RESEARCH, 1982, 61 (08) : 1006 - 1009
  • [46] Histometric Analysis of Bone Repair in Bone-Implant Interface Using a Polylactic/Polyglycolic Acid Copolymer Associated With Implants in Rabbit Tibia
    Freire, Alexandre Rodrigues
    Rossi, Ana Claudia
    Queiroz, Thallita Pereira
    Gulinelli, Jessica Lemos
    Souza, Francisley Avila
    Margonar, Rogerio
    Garcia-Junior, Idelmo Rangel
    Hochuli-Vieira, Eduardo
    Okamoto, Roberta
    JOURNAL OF ORAL IMPLANTOLOGY, 2012, 38 (01) : 449 - 457
  • [47] The Effect of Osteotomy Preparation Techniques and Implant Diameter on Primary Stability and the Bone-Implant Interface of Short Implants (6 mm)
    Koutouzis, Theofilos
    Bembey, Kanika
    Sofos, Stavros
    INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS, 2025, 40 (01) : 27 - 32
  • [48] Immediate implants into periodontally infected sites in dogs. A histomorphometric study of bone-implant interface.
    Marcaccini, AM
    Novaes, AB
    Souza, SLS
    Taba, M
    Grisi, FFM
    Almeida, ALG
    JOURNAL OF DENTAL RESEARCH, 2003, 82 : 289 - 289
  • [49] The effect of alendronate soaking and ultraviolet treatment on bone-implant interface
    Kim, Hyung Soo
    Lee, Jae In
    Yang, Sun Sik
    Kim, Beom Su
    Kim, Bong Chul
    Lee, Jun
    CLINICAL ORAL IMPLANTS RESEARCH, 2017, 28 (09) : 1164 - 1172
  • [50] INFLUENCE OF HEALING TIME ON THE ULTRASONIC RESPONSE OF THE BONE-IMPLANT INTERFACE
    Mathieu, Vincent
    Vayron, Romain
    Soffer, Emmanuel
    Anagnostou, Fani
    Haiat, Guillaume
    ULTRASOUND IN MEDICINE AND BIOLOGY, 2012, 38 (04): : 611 - 618