Activation of the hTAS2R14 Human Bitter-Taste Receptor by (-)-Epigallocatechin Gal late and (-)-Epicatechin Gal late

被引：33
|
作者：
Yamazaki, Toyomi [1 ]
Narukawa, Masataka [2 ]
Mochizuki, Mineko [1 ]
Misaka, Takumi [2 ]
Watanabe, Tatsuo [1 ]
机构：
[1] Univ Shizuoka, Grad Div Nutr & Environm Sci, Suruga Ku, Shizuoka 4228526, Japan
[2] Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2013年 / 77卷 / 09期
关键词：
green tea; catechin; bitter taste; bitter taste receptor; hTAS2R14; GREEN TEA CATECHINS; BLACK TEA; MICE; FAMILY; CELLS;
D O I：
10.1271/bbb.130329
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Tea catechins have strong bitterness and influence the taste of tea. Among the 25 human bitter-taste receptors (TAS2Rs), we found that hTAS2R14 responded to catechins, in addition to hTAS2R39, a known catechin receptor. Although hTAS2R14 responded to (-)-epicatechin gallate and (-)-epigallocatechin gallate, it did not respond to (-)-epicatechin and (-)-epigallocatechin.
引用
收藏
页码：1981 / 1983
页数：3
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