Exploring Human Skin Aging at the Single-Cell Level

被引：2
|
作者：
Mohrin, Mary [1 ]
Jasper, Heinrich [1 ]
机构：
[1] Genentech Inc, Immunol Discovery, 1 DNA Way, San Francisco, CA 94080 USA
来源：
DEVELOPMENTAL CELL | 2021年 / 56卷 / 03期
关键词：
D O I：
10.1016/j.devcel.2021.01.006
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In this issue of Developmental Cell, Zou et al. utilize eyelid samples to examine human skin aging at the single-cell level. They discover photo- and inflammation-related changes already in middle age and find that restoring youthful expression of KLF6 and HES1 may dial back some age-associated changes.
引用
收藏
页码：253 / 254
页数：2
相关论文
共 50 条
  • [41] Instrument-free single-cell resolution of transcriptome in human skin
    Demouche, S.
    Poncin, R.
    Grolleau, C.
    Merandet, M.
    Bergerat, D.
    Majello, S.
    Dimitrova, D.
    Lipin, S.
    Bouaziz, J.
    Le Buanec, H.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2022, 142 (12) : S228 - S228
  • [42] Endothelial cell plasticity at the single-cell level
    Alessandra Pasut
    Lisa M. Becker
    Anne Cuypers
    Peter Carmeliet
    Angiogenesis, 2021, 24 : 311 - 326
  • [43] Endothelial cell plasticity at the single-cell level
    Pasut, Alessandra
    Becker, Lisa M.
    Cuypers, Anne
    Carmeliet, Peter
    ANGIOGENESIS, 2021, 24 (02) : 311 - 326
  • [44] T Cell Fate at the Single-Cell Level
    Buchholz, Veit R.
    Schumacher, Ton N. M.
    Busch, Dirk H.
    ANNUAL REVIEW OF IMMUNOLOGY, VOL 34, 2016, 34 : 65 - 92
  • [45] Mapping Cell Atlases at the Single-Cell Level
    Ye, Fang
    Wang, Jingjing
    Li, Jiaqi
    Mei, Yuqing
    Guo, Guoji
    ADVANCED SCIENCE, 2024, 11 (08)
  • [46] Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin
    Li, Qingyang
    Zhu, Zhenlai
    Wang, Lei
    Lin, Yiting
    Fang, Hui
    Lei, Jie
    Cao, Tianyu
    Wang, Gang
    Dang, Erle
    THERANOSTICS, 2021, 11 (13): : 6461 - 6476
  • [47] Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin
    Li, Q.
    Zhu, Z.
    Wang, L.
    Lin, Y.
    Fang, H.
    Lei, J.
    Cao, T.
    Gang, W.
    Dang, E.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (05) : S104 - S104
  • [48] Resolving the fibrotic niche of human liver cirrhosis at single-cell level
    P. Ramachandran
    R. Dobie
    J. R. Wilson-Kanamori
    E. F. Dora
    B. E. P. Henderson
    N. T. Luu
    J. R. Portman
    K. P. Matchett
    M. Brice
    J. A. Marwick
    R. S. Taylor
    M. Efremova
    R. Vento-Tormo
    N. O. Carragher
    T. J. Kendall
    J. A. Fallowfield
    E. M. Harrison
    D. J. Mole
    S. J. Wigmore
    P. N. Newsome
    C. J. Weston
    J. P. Iredale
    F. Tacke
    J. W. Pollard
    C. P. Ponting
    J. C. Marioni
    S. A. Teichmann
    N. C. Henderson
    Nature, 2019, 575 : 512 - 518
  • [49] Techniques converge to map the developing human heart at single-cell level
    Ragini Phansalkar
    Kristy Red-Horse
    Nature, 2020, 577 (7792) : 629 - 630
  • [50] Resolving the fibrotic niche of human liver cirrhosis at single-cell level
    Ramachandran, P.
    Dobie, R.
    Wilson-Kanamori, J. R.
    Dora, E. F.
    Henderson, B. E. P.
    Luu, N. T.
    Portman, J. R.
    Matchett, K. P.
    Brice, M.
    Marwick, J. A.
    Taylor, R. S.
    Efremova, M.
    Vento-Tormo, R.
    Carragher, N. O.
    Kendall, T. J.
    Fallowfield, J. A.
    Harrison, E. M.
    Mole, D. J.
    Wigmore, S. J.
    Newsome, P. N.
    Weston, C. J.
    Iredale, J. P.
    Tacke, F.
    Pollard, J. W.
    Ponting, C. P.
    Marioni, J. C.
    Teichmann, S. A.
    Henderson, N. C.
    NATURE, 2019, 575 (7783) : 512 - +
12345