The Pfam protein families database

被引：76

作者：

Bateman, A

Birney, E

Durbin, R

Eddy, SR

Howe, KL

Sonnhammer, ELL

机构：

[1] Sanger Ctr, Cambridge CB10 1SA, England

[2] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

[3] Karolinska Inst, Ctr Genom Res, S-17177 Stockholm, Sweden

来源：

NUCLEIC ACIDS RESEARCH | 2000年 / 28卷 / 01期

关键词：

D O I：

10.1093/nar/28.1.263

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the WWW in the UK at http://www.sanger.ac.uk/Software/Pfam/, in Sweden at http://www.cgr.ki.se/Pfam/ and in the US at http:// pfam.wustl.edu/. The latest version (4.3) of Pfam contains 1815 families. These Pfam families match 63% of proteins in SWISS-PROT 37 and TrEMBL 9, For complete genomes Pfam currently matches up to half of the proteins. Genomic DNA can be directly searched against the Pfam library using the Wise2 package.

引用

页码：263 / 266

页数：4

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