Impaired fasting glucose and myocardial infarction

We aimed to examine the associations between classic cardiovascular risk factors and impaired fasting glucose, and fatal and non-fatal myocardial infarction (MI). We evaluated 206 patients (pts), 131 m and 75f, 62+/-11 years old with fatal (43pts) and non-fatal (163pts) MI. Impaired fasting glucose (IFG) (greater than or equal to5.7mmol/l) was present in 93 pts, and the other 113 pts were with fasting glucose <5.7mmol/l (NFG) on the seventh day of addmision. Patients with IFG showed significantly larger infarction size, creatin kinase increment (Max CK activity was higher, p=0.034) and they were more obese(p=0.04). Serum levels of cholesterol, triglycerides, systolic and diastolic blood pressure, as predictors of cardiovascular morbidity and mortality did not differ between groups. Serum cholesterol correlated inversely with infarct size in the IFG group (r= -0.238, p=0.022). There were no differences for early mortality rate or occurance of atrial or ventricular arrhythmia between two groups. This study shows that among non-diabetic pts with MI, those with IFG have greater myocardial necrosis and were more obese. Serum cholesterol, a classic cardiovascular risk factor, is associated with infarct size in IFG group of pts only.