GC-MS ANALYSIS AND IDENTIFICATION OF PHYTOCONSTITUENTS FROM HEXANE EXTRACTS OF ADHATODA VASICA NEES AND ADHATODA BEDDOMEI CB CLARKE LEAVES

被引:0
|
作者
Sundaresan, Nandhini [1 ,2 ]
Kaliappan, Ilango [1 ,2 ]
机构
[1] Interdisciplinary Inst Indian Syst Med IIISM, Div Pharmacognosy & Phytochem, Chengalpattu 603203, Tamil Nadu, India
[2] SRM Inst Sci & Technol SRMIST, SRM Coll Pharm, Dept Pharmaceut Chem, Chengalpattu 603203, Tamil Nadu, India
来源
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2020年 / 11卷 / 12期
关键词
Adhatoda vasica; Adhatoda beddomei; GC-MS; Vasicolinone and methyl commate;
D O I
10.13040/IJPSR.0975-8232.11(12).6342-49
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The medicinal plants, Adhatoda vasica, and Adhatoda beddomei are commonly used in the treatment of several illnesses and respiratory disorders viz., cold, severe cough, chronic bronchitis, asthma and tuberculosis. The present study aimed to identify the phytochemical constituents and quantification of bioactive contents of hexane extracts of these plants, followed by metabolic fingerprinting, which was carried out by GC-MS analysis. Assessment of phytochemical screening showed the presence of various phytochemicals like glycosides, phytosterols, flavonoids, terpenoids, and phenols in hexane extract of A. vasica and A. beddomei. A rapid method has been used for the comparative study of A. vasica and its related plant species A. beddomei using gas chromatography-mass spectrometry (GC-MS). The phytocompounds comparison in two plants by GC-MS was similar in 12 compositions. Squalene, beta-sitosterol, tetratetracontane, and lupeol were the major constituents identified in the hexane extract of A. vasica and A. beddomei. The extracts showed the presence of several phytoconstituents, including bioactive components, and provide reference data for future research of its active constituents.
引用
收藏
页码:6342 / 6349
页数:8
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