AgI-promoted one-pot synthesis of aminoindolizines via sequential Mannich-Grignard addition and intramolecular cyclization in water

被引：6
|
作者：
Guguloth, Veeranna [1 ]
Balaboina, Ramesh [1 ]
Paidakula, Suresh [1 ]
Thirukovela, Narasimha S. [2 ]
Vadde, Ravinder [1 ]
机构：
[1] Kakatiya Univ, Dept Chem, Warangal, Andhra Pradesh, India
[2] Chaitanya Deemed Univ, Dept Chem, Warangal, Andhra Pradesh, India
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2021年 / 58卷 / 03期
关键词：
AQUEOUS-MEDIA; LAMELLARIN-D; CATALYSIS; ALKYNES; ANTICONVULSANT; DERIVATIVES; ANALOGS; ROUTE;
D O I：
10.1002/jhet.4184
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The efficient synthesis of aminoindolizines in ecofriendly water with broad substrate scope from the mild and readily available AgI-catalyzed one-pot three-component reaction of pyridine-2-carboxaldehyde, secondary amines, and terminal alkynes proceeds through the sequential Mannich-Grignard addition as well as intramolecular cyclization was reported for the first time.
引用
收藏
页码：900 / 904
页数：5
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