Chromosome 9p24.1/PD-L1/PD-L2Alterations and PD-L1 Expression and Treatment Outcomes in Patients with Classical Hodgkin Lymphoma Treated with Nivolumab (PD-1 Blockade)

被引:8
|
作者
Roemer, Margaretha G. M. [1 ]
Ligon, Azra H. [2 ]
Engert, Andreas [3 ,4 ]
Younes, Anas [5 ]
Santoro, Armando [6 ,7 ]
Zinzani, Pier Luigi [8 ]
Timmerman, John M. [9 ]
Ansell, Stephen [10 ]
Armand, Philippe [11 ,12 ]
Fanale, Michelle A. [13 ]
Ratanatharathorn, Voravit [14 ]
Kuruvilla, John [15 ]
Cohen, Jonathon B. [16 ]
Collins, Graham P. [17 ]
Savage, Kerry J. [18 ,19 ]
Trneny, Marek [20 ,21 ]
Neuberg, Donna S. [22 ]
Redd, Robert A. [23 ]
Farsaci, Benedetto [24 ]
Kato, Kazunobu [24 ]
Sumbul, Anne [24 ]
Rodig, Scott J. [25 ]
Shipp, Margaret A. [26 ]
机构
[1] Dana Farber Canc Inst, Med Oncol, Boston, MA USA
[2] Brigham & Womens Hosp, Pathol, Boston, MA USA
[3] Univ Hosp Cologne, Dept Internal Med 1, Cologne, Germany
[4] Univ Hosp Cologne, GHSG, Cologne, Germany
[5] Mem Sloan Kettering Canc Ctr, Dept Med, Lymphoma Serv, New York, NY USA
[6] Humanitas Univ, Milan, Italy
[7] Humanitas Res Hosp, Milan, Italy
[8] Univ Bologna, Inst Hematol L & A Seragnoli, Bologna, Italy
[9] UCLA Med Ctr, Los Angeles, CA USA
[10] Mayo Clin, Rochester, MN USA
[11] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA
[12] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA
[13] Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX USA
[14] Barbara Ann Karmanos Canc Inst, Detroit, MI USA
[15] Princess Margaret Canc Ctr, Dept Med Oncol & Hematol, Toronto, ON, Canada
[16] Emory Univ, Winship Canc Inst, Atlanta, GA USA
[17] Churchill Hosp, Oxford Canc & Haematol Ctr, Oxford, England
[18] British Columbia Canc Agcy, Div Med Oncol, Vancouver, BC, Canada
[19] British Columbia Canc Agcy, Ctr Lymphoid Canc, Vancouver, BC, Canada
[20] Charles Univ Prague, Dept Med 1, Prague, Czech Republic
[21] Gen Univ, Dept Med 1, Prague, Czech Republic
[22] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA USA
[23] Dana Farber Canc Inst, Biostat & Computat Biol, Boston, MA USA
[24] Bristol Myers Squibb, Princeton, NJ USA
[25] Dana Farber Harvard Canc Ctr, Dept Pathol, Boston, MA USA
[26] Dana Farber Canc Inst, Boston, MA USA
关键词
D O I
10.1182/blood.V128.22.2923.2923
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2923
引用
收藏
页数:7
相关论文
共 50 条
  • [21] Changes in PD-1 and PD-L1 Expression in Cases with Hodgkin Lymphoma after Chemotherapy
    Paydas, Semra
    Bagir, Emine
    Ergin, Melek
    Seydaoglu, Gulsah
    BLOOD, 2015, 126 (23)
  • [22] PD-1/PD-L1 inhibitors
    Sunshine, Joel
    Taube, Janis M.
    CURRENT OPINION IN PHARMACOLOGY, 2015, 23 : 32 - 38
  • [23] PD-1/PD-L1 in disease
    Kuol, Nyanbol
    Stojanovska, Lily
    Nurgali, Kulmira
    Apostolopoulos, Vasso
    IMMUNOTHERAPY, 2018, 10 (02) : 149 - 161
  • [24] PD-1, PD-L1 and PD-L2 Expression in Mantle Cell Lymphoma and Healthy Population
    Karolova, J.
    Radek, M.
    Helman, K.
    Spacek, M.
    Trneny, M.
    Klener, P.
    FOLIA BIOLOGICA, 2020, 66 (04) : 117 - 122
  • [25] PD-1/ PD-L1 blockade as a novel treatment for colorectal cancer
    Yaghoubi, Neda
    Soltani, Arash
    Ghazvini, Kiarash
    Hassanian, Seyed Mahdi
    Hashemy, Seyed Isaac
    BIOMEDICINE & PHARMACOTHERAPY, 2019, 110 : 312 - 318
  • [26] PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome
    Roemer, Margaretha G. M.
    Advani, Ranjana H.
    Ligon, Azra H.
    Natkunam, Yasodha
    Redd, Robert A.
    Homer, Heather
    Connelly, Courtney F.
    Sun, Heather H.
    Daadi, Sarah E.
    Freeman, Gordon J.
    Armand, Philippe
    Chapuy, Bjoern
    de Jong, Daphne
    Hoppe, Richard T.
    Neuberg, Donna S.
    Rodig, Scott J.
    Shipp, Margaret A.
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (23) : 2690 - +
  • [27] PD-1/PD-L1 blockade in cancer treatment: perspectives and issues
    Hamanishi, Junzo
    Mandai, Masaki
    Matsumura, Noriomi
    Abiko, Kaoru
    Baba, Tsukasa
    Konishi, Ikuo
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2016, 21 (03) : 462 - 473
  • [28] PD-1/PD-L1 blockade in cancer treatment: perspectives and issues
    Junzo Hamanishi
    Masaki Mandai
    Noriomi Matsumura
    Kaoru Abiko
    Tsukasa Baba
    Ikuo Konishi
    International Journal of Clinical Oncology, 2016, 21 : 462 - 473
  • [29] PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome
    Roemer, Margaretha G. M.
    Advani, Ranjana H.
    Ligon, Azra H.
    Natkunam, Yasodha
    Redd, Robert A.
    Homer, Heather
    Connelly, Courtney
    Sun, Heather H.
    Daadi, Sarah E.
    Chapuy, Bjoern
    de Jong, Daphne
    Hoppe, Richard T.
    Neuberg, Donna S.
    Rodig, Scott J.
    Shipp, Margaret A.
    BLOOD, 2015, 126 (23)
  • [30] Erratum to: PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment
    Dimitrios Mathios
    Jacob Ruzevick
    Christopher M. Jackson
    Haiying Xu
    Sagar R. Shah
    Janis M. Taube
    Peter C. Burger
    Edward F. McCarthy
    Alfredo Quinones-Hinojosa
    Drew M. Pardoll
    Michael Lim
    Journal of Neuro-Oncology, 2016, 128 : 183 - 183