Chromosome 9p24.1/PD-L1/PD-L2Alterations and PD-L1 Expression and Treatment Outcomes in Patients with Classical Hodgkin Lymphoma Treated with Nivolumab (PD-1 Blockade)

被引：8

作者：

Roemer, Margaretha G. M. ^{[1
]}

Ligon, Azra H. ^{[2
]}

Engert, Andreas ^{[3
,4
]}

Younes, Anas ^{[5
]}

Santoro, Armando ^{[6
,7
]}

Zinzani, Pier Luigi ^{[8
]}

Timmerman, John M. ^{[9
]}

Ansell, Stephen ^{[10
]}

Armand, Philippe ^{[11
,12
]}

Fanale, Michelle A. ^{[13
]}

Ratanatharathorn, Voravit ^{[14
]}

Kuruvilla, John ^{[15
]}

Cohen, Jonathon B. ^{[16
]}

Collins, Graham P. ^{[17
]}

Savage, Kerry J. ^{[18
,19
]}

Trneny, Marek ^{[20
,21
]}

Neuberg, Donna S. ^{[22
]}

Redd, Robert A. ^{[23
]}

Farsaci, Benedetto ^{[24
]}

Kato, Kazunobu ^{[24
]}

Sumbul, Anne ^{[24
]}

Rodig, Scott J. ^{[25
]}

Shipp, Margaret A. ^{[26
]}

机构：

[1] Dana Farber Canc Inst, Med Oncol, Boston, MA USA

[2] Brigham & Womens Hosp, Pathol, Boston, MA USA

[3] Univ Hosp Cologne, Dept Internal Med 1, Cologne, Germany

[4] Univ Hosp Cologne, GHSG, Cologne, Germany

[5] Mem Sloan Kettering Canc Ctr, Dept Med, Lymphoma Serv, New York, NY USA

[6] Humanitas Univ, Milan, Italy

[7] Humanitas Res Hosp, Milan, Italy

[8] Univ Bologna, Inst Hematol L & A Seragnoli, Bologna, Italy

[9] UCLA Med Ctr, Los Angeles, CA USA

[10] Mayo Clin, Rochester, MN USA

[11] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA

[12] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA

[13] Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX USA

[14] Barbara Ann Karmanos Canc Inst, Detroit, MI USA

[15] Princess Margaret Canc Ctr, Dept Med Oncol & Hematol, Toronto, ON, Canada

[16] Emory Univ, Winship Canc Inst, Atlanta, GA USA

[17] Churchill Hosp, Oxford Canc & Haematol Ctr, Oxford, England

[18] British Columbia Canc Agcy, Div Med Oncol, Vancouver, BC, Canada

[19] British Columbia Canc Agcy, Ctr Lymphoid Canc, Vancouver, BC, Canada

[20] Charles Univ Prague, Dept Med 1, Prague, Czech Republic

[21] Gen Univ, Dept Med 1, Prague, Czech Republic

[22] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA USA

[23] Dana Farber Canc Inst, Biostat & Computat Biol, Boston, MA USA

[24] Bristol Myers Squibb, Princeton, NJ USA

[25] Dana Farber Harvard Canc Ctr, Dept Pathol, Boston, MA USA

[26] Dana Farber Canc Inst, Boston, MA USA

来源：

BLOOD | 2016年 / 128卷 / 22期

关键词：

D O I：

10.1182/blood.V128.22.2923.2923

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2923

引用

页数：7

共 50 条

[1] Co-amplifications of PD-L1/PD-L2 genes (9p24.1) and PD-L1 protein expression in NSCLC patients
Clave, S.
Casadevall, D.
Pijuan, L.
Rodriguez-Rivera, M.
Garcia-Moreno, P.
Taus, A.
Albanell, J.
Espinet, B.
Arriola, E.
Salido, M.
JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (04) : S58 - S58
[2] Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade
Bai, Jie
Gao, Zhitao
Li, Xiang
Dong, Liang
Han, Weidong
Nie, Jing
ONCOTARGET, 2017, 8 (66) : 110693 - 110707
[3] Relevance of host and tumor PD-L1 expression in PD-L1 and PD-1 blockade
Lin, Heng
Wei, Shuang
Vatan, Linda
Kryczek, Ilona
Zou, Weiping
JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
[4] Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphoma
Hollander, Peter
Amini, Rose-Marie
Ginman, Beatrice
Molin, Daniel
Enblad, Gunilla
Glimelius, Ingrid
PLOS ONE, 2018, 13 (09):
[5] Soluble PD-1 and PD-L1 as potential biomarkers for classical Hodgkin lymphoma
da Silva, Priscilla Brito
Real, Juliana Monte
Pinto Ferreira, Ludmila Rodrigues
Esteves, Gustavo H.
Brito, Fabio do Nascimento
Baiocchi, Otavio C. G.
HEMATOLOGICAL ONCOLOGY, 2018, 36 (04) : 709 - 712
[6] PD-L1 expression and PD-1/PD-L1 inhibitors in breast cancer
Monneur, Audrey
Goncalves, Anthony
Bertucci, Francois
BULLETIN DU CANCER, 2018, 105 (03) : 261 - 272
[7] PD-L1 Expression in Mucosal Malignant Melanoma: Implications for PD-1/PD-L1 Blockade Therapy
Lilo, Mohammed
Berry, Sneha
Xu, Haiying
Ogurtsova, Aleksandra
Lipson, Evan
Taube, Janis
MODERN PATHOLOGY, 2015, 28 : 123A - 123A
[8] PD-L1 Expression in Mucosal Malignant Melanoma: Implications for PD-1/PD-L1 Blockade Therapy
Lilo, Mohammed
Berry, Sneha
Xu, Haiying
Ogurtsova, Aleksandra
Lipson, Evan
Taube, Janis
LABORATORY INVESTIGATION, 2015, 95 : 123A - 123A
[9] Expression of PD-1/PD-L1 in children's classical Hodgkin lymphomas
Dilly-Feldis, Marie
Aladjidi, Nathalie
Refait, John K.
Parrens, Marie
Ducassou, Stephane
Rullier, Anne
PEDIATRIC BLOOD & CANCER, 2019, 66 (05)
[10] PD-L1 Expression in Classical Hodgkin Lymphoma in Pediatric Patients
Aoki, Takahiro
Kyushiki, Masashi
Kishimoto, Hiroshi
Yanagi, Masato
Mori, Makiko
Arakawa, Yuki
Hino, Moeko
Shimojo, Naoki
Koh, Katsuyoshi
PEDIATRIC BLOOD & CANCER, 2017, 64 : S102 - S102

← 1 2 3 4 5 →